405939-79-9

Basic information

• Product Name: 4-IODOPYRIDINE-2-CARBOXYLIC ACID
• Synonyms: AKOS BBS-00006014;4-IODO-2-PYRIDINECARBOXYLIC ACID;4-IODOPICOLINIC ACID;4-IODOPYRIDINE-2-CARBOXYLIC ACID;IFLAB-BB F1926-0015;4-Iodopyridine-2-carboxylic acid 96%;4-Iodopyridine-2-carboxylic acid ,97%;4-4-Iodopyridine-2-carboxylic acid
• CAS NO: 405939-79-9
• Molecular Formula: C₆H₄INO₂
• Molecular Weight: 249.01
• Product Categories: blocks;Carboxes;Iodides;Pyridines;pharmacetical;Heterocycle-Pyridine series
• Mol File: 405939-79-9.mol

Chemical Properties

• Melting Point: 164-166
• Boiling Point: 376.234 °C at 760 mmHg
• Flash Point: 181.34 °C
• Appearance: /
• Density: 2.124 g/cm³
• Vapor Pressure: 2.49E-06mmHg at 25°C
• Refractive Index: 1.677
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• PKA: 3.29±0.10(Predicted)
• CAS DataBase Reference: 4-IODOPYRIDINE-2-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-IODOPYRIDINE-2-CARBOXYLIC ACID(405939-79-9)
• EPA Substance Registry System: 4-IODOPYRIDINE-2-CARBOXYLIC ACID(405939-79-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36-37/38/39
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 405939-79-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H4INO2/c7-4-1-2-8-5(3-4)6(9)10/h1-3H,(H,9,10)

Upstream product

• 5470-22-4 4-chloropicolinic acid 
• 98-98-6 2-Picolinic acid 
• 24484-93-3 4-Chloro-pyridine-2-carboxylic acid methyl ester 

Downstream Products

• 640296-23-7 4-{2-[(4-iodo-pyridine-2-carbonyl)-amino]-phenoxy}-phthalic acid dimethyl ester 
• 1244016-83-8 methyl 4-(2-phenylethynyl)pyridine-2-carboxylate 
• 261777-31-5 C₁₇H₂₃NO₄ 

Relevant articles and documents

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The disclosure is directed to compounds identified as allosteric modulators of 5-HT 2CR, as well as pharmaceutical compositions and methods using the same. Certain embodiments also include methods of identifying and methods of synthesizing the compounds. Optimization and development of allosteric 5-HT 2CR modulators that bind sites other than the primary ligand binding site generate novel, highly selective, and potent ligands of 5-HT2CR. Such molecules can be used as small molecule probes for the nervous system and as effective therapeutics for a variety of diseases.

ALLOSTERIC MODULATORS OF 5-HYDROXYTRYPTAMINE 2C RECEPTOR (5-HT2CR)

[000166] Embodiments of the invention are directed to methods of identifying, methods of synthesizing, and compositions identified as allosteric modulators of 5-HT2cR.

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Novel lincomycin derivatives possessing antibacterial activity

Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. The compounds of the subject invention may exhibit potent activities against bacteria, including Gram positive organisms, and may be useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.

LINCOMYCIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY

Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. As the compounds of the subject invention exhibit potent activities against bacteria, including gram positive organisms, they are useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.