40678-33-9Relevant articles and documents
Preparation method of dimemorfan phosphate, and preparation methods of dimemorfan phosphate intermediates
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, (2020/01/12)
The invention relates to a preparation method for dimemorfan phosphate and preparation methods of dimemorfan phosphate intermediates, and belongs to the field of pharmaceutical chemicals. The invention provides the synthesis method of the dimemorfan phosp
Preparation method of dimemorfan phosphate
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Page/Page column 0035; 0036, (2018/09/21)
The invention relates to the field of pharmaceutical chemistry, in particular to a preparation method of a non-addictive central antitussive dimemorfan phosphate. The method is characterized by: taking the basic group dextromethorphan of the drug dextromethorphan hydrobromide marketed for years as the starting raw material, conducting methoxymethylation, and then salifying the product with phosphoric acid to obtain dimemorfan phosphate. The method provided by the invention has the advantages of concise process route, high product purity and low cost, and is suitable for industrial production.