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benzyl 2-(4-fluorophenyl)-4-oxopiperidine-1-carboxylate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1-Piperidinecarboxylic acid, 2-(4-fluorophenyl)-4-oxo-, phenylmethyl ester

    Cas No: 414910-20-6

  • USD $ 1.9-2.9 / Gram

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  • 414910-20-6 Structure
  • Basic information

    1. Product Name: benzyl 2-(4-fluorophenyl)-4-oxopiperidine-1-carboxylate
    2. Synonyms: benzyl 2-(4-fluorophenyl)-4-oxopiperidine-1-carboxylate;1-Piperidinecarboxylic acid, 2-(4-fluorophenyl)-4-oxo-, phenylmethyl ester
    3. CAS NO:414910-20-6
    4. Molecular Formula: C19H18FNO3
    5. Molecular Weight: 327.3495232
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 414910-20-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: benzyl 2-(4-fluorophenyl)-4-oxopiperidine-1-carboxylate(CAS DataBase Reference)
    10. NIST Chemistry Reference: benzyl 2-(4-fluorophenyl)-4-oxopiperidine-1-carboxylate(414910-20-6)
    11. EPA Substance Registry System: benzyl 2-(4-fluorophenyl)-4-oxopiperidine-1-carboxylate(414910-20-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 414910-20-6(Hazardous Substances Data)

414910-20-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 414910-20-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,1,4,9,1 and 0 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 414910-20:
(8*4)+(7*1)+(6*4)+(5*9)+(4*1)+(3*0)+(2*2)+(1*0)=116
116 % 10 = 6
So 414910-20-6 is a valid CAS Registry Number.

414910-20-6Downstream Products

414910-20-6Relevant articles and documents

Discovery of BAY-298 and BAY-899: Tetrahydro-1,6-naphthyridine-Based, Potent, and Selective Antagonists of the Luteinizing Hormone Receptor Which Reduce Sex Hormone Levels in Vivo

Wortmann, Lars,Lindenthal, Bernhard,Muhn, Peter,Walter, Alexander,Nubbemeyer, Reinhard,Heldmann, Dieter,Sobek, Lothar,Morandi, Federica,Schrey, Anna K.,Moosmayer, Dieter,Günther, Judith,Kuhnke, Joachim,Koppitz, Marcus,Lücking, Ulrich,R?hn, Ulrike,Sch?fer, Martina,Nowak-Reppel, Katrin,Kühne, Ronald,Weinmann, Hilmar,Langer, Gernot

, p. 10321 - 10341 (2019/11/21)

The human luteinizing hormone receptor (hLH-R) is a member of the glycoprotein hormone family of G-protein-coupled receptors (GPCRs), activated by luteinizing hormone (hLH) and essentially involved in the regulation of sex hormone production. Thus, hLH-R

A consecutive process for C-C and C-N bond formation with high enantio-and diastereo-control: Direct reductive amination of chiral ketones using hydrogenation catalysts

Gilbert, Sophie H.,Viseur, Virginie,Clarke, Matthew L.

supporting information, p. 6409 - 6412 (2019/06/07)

High diastereoselectivity was observed in the Rh-catalysed reductive amination of 3-arylcyclohexanones to form tertiary amines. This was incorporated into a one-pot enantioselective conjugate addition and diastereoselective reductive amination, including an example of assisted tandem catalysis.

4-PIPERIDIN-N-(PYRIMIDIN-4-YL)CHROMAN-7-SULFONAMIDE DERIVATIVES AS SODIUM CHANNEL INHIBITORS

-

Page/Page column 38; 41, (2018/10/19)

The invention provides 4-piperidin-chroman-7-sulfonamide derivatives and salts thereof that are sodium channel modulators, as well as compositions containing such a compound or salt and therapeutic methods for using such a compound, salt, or composition.

THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF

-

Page/Page column 283; 285, (2017/08/01)

The invention provides a compound of formula: or a salt thereof, wherein the variables RAA, n, ring A, ring B, R1a, R1b, R2, R3, R4, R5, R6, R7, R8, and R9 have the meaning as described herein, and compositions containing such compounds and methods for using such compounds and compositions.

BENZOXAZEPINES AS INHIBITORS OF P13K/MTOR AND METHODS OF THEIR USE AND MANUFACTURE

-

Page/Page column 162, (2012/06/15)

The invention is directed to Compounds of Formula I: and pharmaceutically acceptable salts or solvates thereof, as well as methods of making and using the compounds. 9936396.1

BENZOXAZEPINES AS INHIBITORS OF MTOR AND METHODS OF THEIR USE AND MANUFACTURE

-

Page/Page column 37, (2010/12/26)

The invention is directed to inhibitors of mTOR and pharmaceutically acceptable salts or solvates thereof, as well as methods of using them. The inhibitors are generally of structural formula wherein the combination of R1 and R2 are

BENZOXAZEPINES AS INHIBITORS OF PI3K/m TOR AND METHODS OF THEIR USE AND MANUFACTURE

-

Page/Page column 127, (2010/12/26)

The invention is directed to Compounds of Formula (I): the invention provides compounds that inhibit, regulate, and/or modulate P13K and/or mTOR that are useful in the treatment of hyperproliferative diseases, such as cancer, in mammals. This invention al

Discovery of a novel sulfonamide-pyrazolopiperidine series as potent and Efficacious γ-Secretase Inhibitors

Ye, Xiaocong M.,Konradi, Andrei W.,Smith, Jenifer,Xu, Ying-Zi,Dressen, Darren,Garofalo, Albert W.,Marugg, Jennifer,Sham, Hing L.,Truong, Anh P.,Jagodzinski, Jacek,Pleiss, Michael,Zhang, Hongbin,Goldbach, Erich,Sauer, John-Michael,Brigham, Elizabeth,Bova, Michael,Basi, Guriqbal S.

scheme or table, p. 2195 - 2199 (2010/07/05)

Discovery of a series of pyrazolopiperidine sulfonamide based γ-secretase inhibitors and its SAR evolution is described. Significant increases in APP potency on the pyrazolopiperidine scaffold over the original N-bicyclic sulfonamide scaffold were achieved and this potency increase translated in an improved in vivo efficacy.

5-(ARYLSULFONYL)-PYRAZOLOPIPERIDINES

-

Page/Page column 131, (2010/11/27)

The invention provides N-cyclic sulfonamido compounds of Formula (I) wherein A, B, R1, R1a, R2, R2a, R3 and R3a are as described in the specification. Compounds of Formula (I) are useful in treating or preventing cognitive disorders, such as Alzheimer 's disease. The invention also encompasses pharmaceutical compositions comprising compounds of Formula (I), methods of preparing compounds of formula (I), and methods of treating cognitive disorders, such as Alzheimer's disease.

Enantioselective synthesis of 2-aryl-4-piperidones via rhodium/ phosphoramidite-catalyzed conjugate addition of arylboroxines

Jagt, Richard B. C.,De Vries, Johannes G.,Feringa, Ben L.,Minnaard, Adriaan J.

, p. 2433 - 2435 (2007/10/03)

(Chemical Equation Presented) The highly enantioselective synthesis of 2-aryl-4-piperidones by rhodium/phosphoramidite-catalyzed conjugate addition of arylboroxines to 2,3-dihydro-4-pyridones is described. Both enantiomers of a variety of products with sterically and electronically different R substituents were obtained in high isolated yield and with excellent enantioselectivity up to 99%.

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