41960-47-8

Basic information

• Product Name: 2-CYANO-5-IODOPYRIDINE
• Synonyms: 2-CYANO-5-IODOPYRIDINE;5-iodopyridine-2-carbonitrile;5-iodo-2-Pyridinecarbonitrile
• CAS NO: 41960-47-8
• Molecular Formula: C₆H₃IN₂
• Molecular Weight: 230.01
• Mol File: 41960-47-8.mol

Chemical Properties

• Boiling Point: 314.3 °C at 760 mmHg
• Flash Point: 143.9 °C
• Appearance: /
• Density: 2.04 g/cm³
• Vapor Pressure: 0.000469mmHg at 25°C
• Refractive Index: 1.669
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: -2.34±0.10(Predicted)
• CAS DataBase Reference: 2-CYANO-5-IODOPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CYANO-5-IODOPYRIDINE(41960-47-8)
• EPA Substance Registry System: 2-CYANO-5-IODOPYRIDINE(41960-47-8)

Safety Data

• Hazardous Substances Data: 41960-47-8(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
2-Cyano-5-iodopyridine is used as a versatile building block for the preparation of various pharmaceuticals, agrochemicals, and other fine chemicals. Its unique structure allows for the synthesis of a wide range of compounds with potential applications in different industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Cyano-5-iodopyridine is used as a key intermediate in the synthesis of biologically active molecules. Its presence in the molecular structure can contribute to the development of new drugs with improved therapeutic properties.
Used in Agrochemical Industry:
2-Cyano-5-iodopyridine is employed as a reagent in the production of heterocyclic compounds, which are often found in agrochemicals. These heterocyclic compounds can be used as pesticides, herbicides, or other agricultural chemicals to protect crops and enhance agricultural productivity.
Used in Material Science:
2-Cyano-5-iodopyridine has been studied for its potential applications in material science. Its unique structural properties may contribute to the development of new materials with specific properties, such as conductivity, magnetism, or optical characteristics.
Used in Medicinal Chemistry:
In medicinal chemistry, 2-Cyano-5-iodopyridine is used as a precursor in the synthesis of biologically active molecules. Its presence in the molecular structure can enhance the pharmacological properties of the resulting compounds, leading to the development of more effective drugs for various diseases and conditions.

InChI:InChI=1/C6H3IN2/c7-5-1-2-6(3-8)9-4-5/h1-2,4H

Upstream product

• 97483-77-7 2-Cyano-5-bromopyridine 
• 55338-73-3 5-amino-2-cyanopyridine 

Downstream Products

• 78760-60-8 5-(benzyloxy)pyridine-2-carbonitrile 

Relevant articles and documents

DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-α]IMIDAZOLE-3- CARBOXYLIC ACID AMIDES

Derivatives of 6,7-dihydro-5H-imidazo[1,2-α]imidazole-3-carboxylic acid amide exhibit good inhibitory effect upon the interaction of CAMs and Leukointegrins and are thus useful in the treatment of inflammatory disease.

A simple Cu-catalyzed coupling approach to substituted 3-pyridinol and 5-pyrimidinol antioxidants

(Chemical Equation Presented) A convenient approach to 3-pyridinols and 5-pyrimidinols via a two-step Cu-catalyzed benzyloxylation/catalytic hydrogenation sequence is presented. The corresponding 3-pyridinamines and 5-pyrimidinamines can be prepared in an analogous sequence utilizing benzylamine in lieu of benzyl alcohol. The radical-scavenging ability of these derivatives are preliminarily explored and reveal that the increased acidities of the pyridinols and pyrimidinols render them susceptible to more significant kinetic solvent effects when compared to phenols.