41999-70-6

Basic information

• Product Name: 2-[(3-aminopropyl)methylamino]ethanol
• Synonyms: 2-[(3-aminopropyl)methylamino]ethanol;N-Methyl-N-(2-hydroxyethyl)-1,3-propanediamine;Ethanol, 2-[(3-aminopropyl)methylamino]- (6CI,7CI,9CI);AMINOPROPYLMONOMETHYLETHANOLAMINE;FENTAMINE APMMEA;(3-Aminopropyl)(2-hydroxyethyl)methylamine;N-(2-Hydroxyethyl)-N-methyl-1,3-propylenediamine;N-(3-Aminopropyl)-N-(2-hydroxyethyl)methylamine
• CAS NO: 41999-70-6
• Molecular Formula: C₆H₁₆N₂O
• Molecular Weight: 132.20404
• EINECS: 255-615-9
• Product Categories: AMINETERTIARY
• Mol File: 41999-70-6.mol

Chemical Properties

• Boiling Point: 229℃
• Flash Point: 92℃
• Appearance: /
• Density: 0.971
• Vapor Pressure: 0.014mmHg at 25°C
• Refractive Index: 1.4781
• PKA: 14.76±0.10(Predicted)
• CAS DataBase Reference: 2-[(3-aminopropyl)methylamino]ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(3-aminopropyl)methylamino]ethanol(41999-70-6)
• EPA Substance Registry System: 2-[(3-aminopropyl)methylamino]ethanol(41999-70-6)

Safety Data

• Hazardous Substances Data: 41999-70-6(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
2-[(3-aminopropyl)methylamino]ethanol is used as a reagent or intermediate in chemical synthesis for its ability to participate in a range of chemical reactions due to its amine and alcohol functional groups.
Used in Coatings:
In the coatings industry, 2-[(3-aminopropyl)methylamino]ethanol is used as a component in the formulation of various types of coatings, leveraging its chemical properties to enhance the performance and characteristics of the final product.
Used in Biocides:
2-[(3-aminopropyl)methylamino]ethanol is employed as a biocide, where its amine and alcohol groups contribute to its antimicrobial properties, making it suitable for use in products designed to control or prevent the growth of microorganisms.
Used in Pharmaceutical Products:
In the pharmaceutical industry, 2-[(3-aminopropyl)methylamino]ethanol is used as a reagent or intermediate in the synthesis of various pharmaceutical compounds, taking advantage of its unique chemical structure to create new drug molecules.

InChI:InChI=1/C6H16N2O/c1-8(5-6-9)4-2-3-7/h9H,2-7H2,1H3

Upstream product

• 109-83-1 (2-hydroxyethyl)(methyl)amine 
• 107-13-1 acrylonitrile 
• 33759-44-3 3-<(2-hydroxyethyl)amino>propionitrile 
• 34508-82-2 monomethylethanolaminopropionitrile 

Downstream Products

• 31501-33-4 N-oleoylaminopropyl-N-hydroxyethyl-N-methylamine 
• 153075-23-1 N-oleoylaminopropyl-N-oleoyloxyethyl-N-methylamine 
• 4318-37-0 1-Methylhomopiperazine 

Relevant articles and documents

N,N,N'-trimethyl-N'-aminopropyldiaminoethylether

The invention provides two synthetic methods for technologically producing a novel polyurethane catalyst N,N,N'-trimethyl-N'-aminopropyldiaminoethylether. A method I is characterized by using trimethyldiaminoethylether as a raw material to react with acrylonitrile, then hydrogenating the product under the condition of catalysts including skeletal nickel, palladium-carbon, platinum-carbon, ruthenium-carbon, and the like, and carrying out separation, thus obtaining the target product. A method II is characterized by condensing dimethylethanolamine and N-methyl-N-aminopropylethanolamine and carrying out separation, thus obtaining the target product.

PROCESS FOR THE PRODUCTION OF AMINOPROPYLMETHYLETHANOLAMINE

A new process for the production of APMMEA (aminopropylmethylethanolamine) is proposed. This process comprises at least 2 steps in which MEAPN (monomethylethanolaminopropionitrile) is first produced from MMEA (monomethylethanol amine) and ACN (acrylonitrile) and then said MEAPN is hydrogenated to obtain the corresponding amine, the APMMEA compound. APMMEA may be then eventually purified by several known process, notably by distillation.

Synthesis and DNA-Sequence Selectivity of a Series of Mono- and Difunctional 9-Aminoacridine Nitrogen Mustards

The aim of this work was to identify nitrogen mustards that would react selectively with DNA, particularly in G-rich regions.A series of mono- and difunctional nitrogen mustards was synthesized in which the (2-chloroethyl)amino functions were connected to the N9 of 9-aminoacridine by way of a spacer chain consisting of two to six methylene units.The length of the spacer chain connecting the alkylating and putative DNA-intercalating groups was found to affect the preference for the alkylation of different guanine-N7 positions in a DNA sequence.All of the compounds reacted preferentially at G's that are followed by G as do most other types of nitrogen mustards, but the degree of selectivity was greater.The compounds reacted at much lower concentrations than were required for comparable reaction by mechlorethamine (HN2), consistent with initial noncovalent binding to DNA prior to guanine-N7 alkylation.The degree of DNA-sequance selectivity increased as the spacer-chain length decrease below four methylene units.Most strikingly, long spacer compounds reacted strongly at 5'-GT-3' sequences, whereas this reaction was almost completely suppressed when the spacer length was reduced to two or three methylenes.Mono- and difunctional compounds of a given spacer length showed no consistent difference in DNA-sequence preference.