42048-11-3

Basic information

• Product Name: 2-CHLORO-6-IODOTOLUENE
• Synonyms: BUTTPARK 121\11-22;2-CHLORO-6-IODOTOLUENE;1-Chloro-3-iodo-2-methylbenzene;2-Chloro-6-iodotoluene,98%;6-CHLORO-2-IODOTOLUENE ;1-Iodo-2-methyl-3-chlorobenzene;Chloro-6-iodotoluene;2-Iodo-6-chlorotoluene
• CAS NO: 42048-11-3
• Molecular Formula: C₇H₆ClI
• Molecular Weight: 252.48
• Product Categories: Halogen toluene;Chlorine Compounds;Iodine Compounds
• Mol File: 42048-11-3.mol

Chemical Properties

• Melting Point: 11°C
• Boiling Point: 119-120°C 15mm
• Flash Point: 119-120°C/15mm
• Appearance: /
• Density: 1,82 g/cm3
• Vapor Pressure: 0.0513mmHg at 25°C
• Refractive Index: 1.6273
• Storage Temp.: Refrigerated.
• Sensitive: Light Sensitive
• BRN: 2433704
• CAS DataBase Reference: 2-CHLORO-6-IODOTOLUENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-6-IODOTOLUENE(42048-11-3)
• EPA Substance Registry System: 2-CHLORO-6-IODOTOLUENE(42048-11-3)

Safety Data

• Hazard Codes: Xi,N
• Statements: 36/37/38-50/53-41-37/38
• Safety Statements: 26-36/37/39-61-60-39-37
• HazardClass: IRRITANT
• Hazardous Substances Data: 42048-11-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Chloro-6-iodotoluene is used as a key intermediate in the synthesis of pharmaceuticals for its ability to be incorporated into complex organic molecules, contributing to the development of new drugs with specific therapeutic properties.
Used in Pesticide Industry:
In the pesticide industry, 2-Chloro-6-iodotoluene is utilized as a building block in the creation of various agrochemicals, enhancing the effectiveness of pest control agents and contributing to agricultural productivity.
Used in Organic Synthesis Research:
2-Chloro-6-iodotoluene is employed as a research compound in organic synthesis, allowing scientists to explore its reactivity and potential applications in the development of novel organic compounds for various industries.

InChI:InChI=1/C7H6ClI/c1-5-6(8)3-2-4-7(5)9/h2-4H,1H3

Upstream product

• 87-60-5 3-chloro-2-methylbenzenamine 
• 95-49-8 2-methylchlorobenzene 

Downstream Products

• 1035263-31-0 2-(bromomethyl)-1-chloro-3-iodobenzene 
• 131070-57-0 (E)-5-Phenyl-hexa-2,5-dienoic acid methyl ester 
• 139553-32-5 3-(2-Iodo-6-chlorophenyl)propionic acid 
• 1071212-41-3 3-(2-Chloro-6-iodo-phenyl)-propionic acid ethyl ester 
• 1001197-89-2 6-chloro-7-methyl-1-(4-nitrophenyl)indoline 
• 1072800-93-1 4-benzyl-1-chloro-2-methylbenzene 
• 1093172-97-4 3-(3-chloro-2-methylphenyl)prop-2-yn-1-ol 
• 28314-05-8 1-chloro-9H-fluorene 

Relevant articles and documents

N-Iodosuccinimide (NIS) in Direct Aromatic Iodination

N-Iodosuccinimide (NIS) in pure trifluoroacetic acid (TFA) offers a time-efficient and general method for the iodination of a wide range of mono- and disubstituted benzenes at room temperature, as demonstrated in this paper. The starting materials were generally converted into mono-iodinated products in less than 16 hours at room temperature, without byproducts. A few deactivated substrates needed addition of sulfuric acid to increase the reaction rate. Another exception was methoxybenzenes that preferentially were iodinated by NIS in acetonitrile with only catalytic amounts of TFA.

METHOD OF PRODUCING IODIZING AGENT, AND METHOD OF PRODUCING AROMATIC IODINE COMPOUND

A method of the present invention, for producing an iodizing agent, includes the step of electrolyzing iodine molecules in a solution by using an acid as a supporting electrolyte. This realizes (i) a method of producing an iodine cation suitable for use as an iodizing agent that does not require a sophisticated separation operation after iodizing reaction is completed, and (ii) an electrolyte used in the method. Further, a method of the present invention, for producing an aromatic iodine compound, includes the step of causing an iodizing agent, and an aromatic compound whose nucleus has one or more substituent groups and two or more hydrogen atoms, to react with each other under the presence of a certain ether compound. This realizes such a method of producing an aromatic iodine compound that position selectivity in iodizing reaction of an aromatic compound is improved.