423178-18-1

Basic information

• Product Name: 2-(CARBOXYMETHYL)-5-IODOBENZOIC ACID
• Synonyms: 2-(CARBOXYMETHYL)-5-IODOBENZOIC ACID
• CAS NO: 423178-18-1
• Molecular Formula: C9H7IO4
• Molecular Weight: 306.05
• Mol File: 423178-18-1.mol

Chemical Properties

• Melting Point: 280 °C
• Boiling Point: 439.3±35.0 °C(Predicted)
• Appearance: /
• Density: 2.020±0.06 g/cm3(Predicted)
• PKA: 3.41±0.36(Predicted)
• CAS DataBase Reference: 2-(CARBOXYMETHYL)-5-IODOBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(CARBOXYMETHYL)-5-IODOBENZOIC ACID(423178-18-1)
• EPA Substance Registry System: 2-(CARBOXYMETHYL)-5-IODOBENZOIC ACID(423178-18-1)

Safety Data

• Hazardous Substances Data: 423178-18-1(Hazardous Substances Data)

Usage

Uses

Used in Biochemistry and Molecular Biology:
2-(carboxymethyl)-5-iodobenzoic acid is used as a fluorescent probe for detecting reactive oxygen species in biological systems, which is crucial for understanding oxidative stress and its implications on cellular processes.
Used in Imaging Techniques:
2-(carboxymethyl)-5-iodobenzoic acid is employed as a tracer in imaging techniques to visualize and track certain cellular processes, providing insights into the dynamics of cell signaling pathways and the effects of oxidative stress.
Used in Drug Delivery Systems:
While not explicitly mentioned in the provided materials, given its properties, 2-(carboxymethyl)-5-iodobenzoic acid could potentially be used in the development of drug delivery systems, particularly for targeted therapies where the visualization of drug distribution and action at the cellular level is required.
Used in Antioxidant Research:
2-(carboxymethyl)-5-iodobenzoic acid is used as a research tool in antioxidant studies, helping to identify and understand the mechanisms of action of antioxidants in countering oxidative stress.

Upstream product

• 14192-12-2 2,5-diiodobenzoic acid 
• 141-97-9 ethyl acetoacetate 
• 1092801-73-4 2-benzyloxy-7-iodoisoquinoline-1,3(2H,4H)-dione 
• 22901-69-5 5-amino-2-(carboxymethyl)benzoic acid 

Relevant articles and documents

Synthesis, biological evaluation and molecular modeling of 2-Hydroxyisoquinoline-1,3-dione analogues as inhibitors of HIV reverse transcriptase associated ribonuclease H and polymerase

Human immunodeficiency virus (HIV) reverse transcriptase (RT) associated ribonuclease H (RNase H) remains the only virally encoded enzymatic function not clinically validated as an antiviral target. 2-Hydroxyisoquinoline-1,3-dione (HID) is known to confer

The design, synthesis and biological evaluations of C-6 or C-7 substituted 2-hydroxyisoquinoline-1,3-diones as inhibitors of hepatitis C virus

C7-Substituted 2-hydroxyisoquinoline-1,3-diones inhibit the strand transfer of HIV integrase (IN) and the reverse-transcriptase-associated ribonuclease H (RNH). Hepatitis C virus (HCV) NS5B polymerase shares a similar active site fold to RNH and IN, sugge

NOVEL INHIBITORS OF FLAVIVIRUS REPLICATION

The present invention relates to a series of novel compounds, methods to prevent or treat viral infections by using the novel compounds, processes for preparation of the compounds, their use to treat or prevent viral infections and their use to manufacture a medicine to treat or prevent viral infections, particularly infections with viruses belonging to the family of the Flaviviridae and more preferably infections with Hepatitis C virus (HCV). The present invention also relates to the novel compounds for use as a medicine, more preferably for use as a medicine for the prevention or treatment of viral infections, preferably infections with viruses belonging to the family of the Flaviviridae.

Design, synthesis, and biological evaluation of a series of 2-hydroxyisoquinoline-1,3(2H,4H)-diones as dual inhibitors of human immunodeficiency virus type 1 integrase and the reverse transcriptase RNase H domain

We report herein the synthesis of a series of 19 2-hydroxyisoquinoline-1, 3(2H,4H)-dione derivatives variously substituted at position 7 aimed at inhibiting selectively two-metal ion catalytic active sites. The compounds were tested against HIV-1 reverse

Aqueous organotin chemistry: Part 3 - Triphenyltin hydride and di-n-butyltin dichloride mediated nucleophilic substitution of 2-iodobenzoates in water

This paper demonstrates the nucleophilic displacement of the iodine in 2-iodobenzoates mediated by triphenyltin hydride and di-n-butyltin dichloride in water.