Potent oxindole based human β3 adrenergic receptor agonists
The synthesis and biological evaluation of a series of oxindole β3 adrenergic receptor agonists is described. A modulation of rat atrial tachycardia was observed with substitution at the 3-position of the oxindole moiety.
Stevens, F. Craig,Bloomquist, William E.,Borel, Anthony G.,Cohen, Marlene L.,Droste, Christine A.,Heiman, Mark L.,Kriauciunas, Aidas,Sall, Daniel J.,Tinsley, Frank C.,Jesudason, Cynthia D.
p. 6270 - 6273
(2008/09/17)
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