42541-99-1

Basic information

• Product Name: (R)-1-Iodo-(E)-1-octen-3-ol
• Synonyms: (1E,3R)-1-Iodo-1-octen-3-ol;(R)-1-Iodo-(E)-1-octen-3-ol
• CAS NO: 42541-99-1
• Molecular Formula: C8H15IO
• Molecular Weight: 254.11
• Mol File: 42541-99-1.mol

Chemical Properties

• Boiling Point: 258 ºC
• Flash Point: 110 ºC
• Appearance: /
• Density: 1.486
• Refractive Index: 1.54
• CAS DataBase Reference: (R)-1-Iodo-(E)-1-octen-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-Iodo-(E)-1-octen-3-ol(42541-99-1)
• EPA Substance Registry System: (R)-1-Iodo-(E)-1-octen-3-ol(42541-99-1)

Safety Data

• Hazardous Substances Data: 42541-99-1(Hazardous Substances Data)

Usage

Uses

Used in Flavoring Industry:
(R)-1-Iodo-(E)-1-octen-3-ol is used as a flavoring agent for its distinct musty and earthy aroma, enhancing the sensory experience of food products.
Used in Organic Synthesis:
(R)-1-Iodo-(E)-1-octen-3-ol is utilized as a reagent in organic chemistry reactions, contributing to the synthesis of other organic compounds.
Used in Agricultural Research:
(R)-1-Iodo-(E)-1-octen-3-ol is studied for its potential antimicrobial properties, which could be beneficial in the development of new treatments or preventive measures against various pathogens in agriculture.
Used in Medical Research:
(R)-1-Iodo-(E)-1-octen-3-ol is also of interest in the medical field due to its potential insecticidal properties, which may lead to the development of new strategies for pest control and disease prevention.

InChI:InChI=1/C8H15IO/c1-2-3-4-5-8(10)6-7-9/h6-8,10H,2-5H2,1H3/b7-6+/t8-/m1/s1

Upstream product

• 128241-51-0 (+)-(3R)-3-(O-tert-butyldimethylsilyl)-1-octyne 
• 32556-70-0 (R)-1-octyn-3-ol 
• 82510-25-6 (R,E)-tert-butyl(1-iodooct-1-en-3-yloxy)dimethylsilane 
• 139400-21-8 (E)-1-Iodo-3-propionyloxy-1-octene 
• 14402-93-8 dipentylzinc 
• 81925-30-6 (E)-3-(tri-n-butylstannyl)-2-propenal 
• 39178-64-8 (E)-1-iodo-1-octen-3-one 

Downstream Products

• 32556-70-0 (R)-1-octyn-3-ol 
• 32556-71-1 1-octyn-3-ol 

Relevant articles and documents

Total synthesis of halicholactone and neohalicholactone

New total syntheses of the marine oxylipins halicholactone and neohalicholactone are presented. The key building blocks were synthesized utilizing chemoenzymatic methods.

Total synthesis of (-)-halicholactone

A convergent total synthesis of halicholactone (1), 5-lipoxygenase inhibitor, using (1S, 5S, 6R)-5-hydroxybicyclo[4.1.0]-heptan-2-one (7) as a chiral building block is described. Z-Selective RCM reaction was the key step to construct the nine-membered unsaturated lactone linkage of 1.

A Lipase Mediated Asymmetric Hydrolysis of 3-Acyloxy-1-octynes and 3-(E)-Acyloxy-1-octenes

Optical resolution of 3-propionyloxy-1-trimethylsilyl-1-octyne or 3-(E)-propionyloxy-1-octene via lipase-mediated hydrolysis gave optically pure (S)-1-trimethylsilyl-1-octyn-3-ol and (R)-(E)-1-iodo-1-octen-3-ol, respectively, in which a reversal of enantio-selectivity for hydrolysis was observed between 3-propionyloxy-1-octyn and its 1-trimethylsilylated derivative, and the effect of the acyl groups on the enantio-discrimination was also investigated.

A new system for catalytic enantioselective reduction of achiral ketones to chiral alcohols. Synthesis of chiral α-hydroxy acids

The reduction of a variety of achiral ketones with catecholborane as stoichiometric reductant and 0.1 equiv of oxazaborolidine 2 as catalyst in toluene at -78°C proceeds in > 95% yield and with enantioselectivities in the range 30:1 to 9:1, depending on s

(+)-1(S),5(R),8(S)-8-PHENYL-2-AZABICYCLOOCTAN-8-OL N,O-METHYLBORONATE (2) AND ITS ENANTIOMER, CHIRAL CHEMZYMES WHICH SERVE AS CATALYSTS FOR THEIR OWN ENANTIOSELECTIVE SYNTHESIS

An efficient synthesis of (+)-1(S),5(R),8(S)-8-phenyl-2-azabicyclooctan-8-ol (1) and its enantiomer is described.The B-methyloxaborolidine derivatives (2) of these amino alcohols are excellent catalysts (chemzymes) for the enantioselective reductio