39178-64-8

Basic information

• Product Name: trans-1-Iodo-1-octen-3-one
• Synonyms: (E)-1-Iodo-1-octen-3-one;trans-1-Iodo-1-octen-3-one
• CAS NO: 39178-64-8
• Molecular Formula: C₈H₁₃IO
• Molecular Weight: 252.09
• Mol File: 39178-64-8.mol
• Article Data: 4

Chemical Properties

• Melting Point: 37.7-38.4 ºC
• Boiling Point: 256 ºC
• Flash Point: 108 ºC
• Appearance: /
• Density: 1.481
• Vapor Pressure: 0.016mmHg at 25°C
• Refractive Index: 1.525
• CAS DataBase Reference: trans-1-Iodo-1-octen-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: trans-1-Iodo-1-octen-3-one(39178-64-8)
• EPA Substance Registry System: trans-1-Iodo-1-octen-3-one(39178-64-8)

Safety Data

• Hazardous Substances Data: 39178-64-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H13IO/c1-2-3-4-5-8(10)6-7-9/h6-7H,2-5H2,1H3/b7-6+

Upstream product

• 27593-19-7 oct-1-yn-3-one 
• 100-52-7 benzaldehyde 

Downstream Products

• 39647-93-3 (S)-(E)-(+)-1-Iodo-1-octen-3-ol 
• 42541-99-1 (R)-(E)-1-Iodo-1-octene-3-ol 
• 29478-39-5 (E)-1-phenyloct-1-en-3-one 
• 116414-84-7 (R)-1-((2R,3R)-3-Iodo-oxiranyl)-hexan-1-ol 
• 104995-81-5 E-(S)-(+)-1-phenyloct-1-en-3-ol 
• 52418-91-4 (E)-1-iodo-3-(triphenylmethoxy)-1-octene 
• 55756-45-1 3-(p-anisyldiphenylmethoxy)-trans-1-octenyllithium 
• 60950-73-4 3-triphenylmethoxy-trans-1-octenyl lithium 
• 1428189-10-9 C₂₄H₃₂O₂ 
• 51953-95-8 7-[(1S,2S)-2-((E)-3-Hydroxy-3-methyl-oct-1-enyl)-5-oxo-cyclopentyl]-heptanoic acid 
• 21269-27-2 (+/-)-15-epi-11-deoxyprostaglandin E₁ 
• 52487-91-9 1-iodo-3-(p-anisyldiphenylmethoxy)-trans-1-octene 
• 3434-33-1 prostaglandin E₁ methyl ester 
• 745-65-3 ALPROSTADIL 

Relevant articles and documents

Stereoselective preparation of functionalized acyclic alkenylmagnesium reagents using i-PrMgCl-LiCl

(Chemical Equation Presented) Acyclic functionalized alkenyl iodides are converted with high stereoselectivity to the corresponding functionalized alkenylmagnesium derivatives by the reaction with i-PrMgCl-LiCl between -40 and -20°C. Functional groups such as a nitrile, chloride, iodide, and ester are readily tolerated. The conversion of an alkenyl iodide bearing a keto group to the corresponding silylated cyanohydrin allows preparation of the corresponding Grignard reagent affording, after acylation and deprotection, unsaturated 1,4-diketones.

ALDOL REACTION OF ALLENOLATES GENERATED VIA 1,4-ADDITION OF IODIDE ANION OR ITS EQUIVALENT TO α,β-ACETYLENIC KETONES

TMSI, Et2AlI, and (n-Bu)4NI/TiCl4 smoothly added to α,β-acetylenic ketones in a 1,4-fashion to yield allenolates 2, which reacted with aldehydes providing aldol adducts in good overall yield.A high Z-stereoselectivity was achieved by use of (n-Bu)4NI/TiCl4 at -78 deg C, while a high E-stereoselectivity occured at 0 deg C.