42564-41-0

Basic information

• Product Name: 4-METHYLAMINO-3-NITRO-BENZALDEHYDE
• Synonyms: 4-(Methylamino)-3-nitrobenzaldehyde
• CAS NO: 42564-41-0
• Molecular Formula: C₈H₈N₂O₃
• Molecular Weight: 180.16
• Mol File: 42564-41-0.mol

Chemical Properties

• Boiling Point: 341.5 °C at 760 mmHg
• Flash Point: 160.3 °C
• Appearance: /
• Density: 1.36 g/cm³
• Vapor Pressure: 8.03E-05mmHg at 25°C
• Refractive Index: 1.664
• CAS DataBase Reference: 4-METHYLAMINO-3-NITRO-BENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHYLAMINO-3-NITRO-BENZALDEHYDE(42564-41-0)
• EPA Substance Registry System: 4-METHYLAMINO-3-NITRO-BENZALDEHYDE(42564-41-0)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 42564-41-0(Hazardous Substances Data)

Usage

Uses

Used in Chemical Research and Development:
4-Methylamino-3-Nitro-Benzaldehyde is used as a reagent for the synthesis of other complex compounds, contributing to the advancement of chemical research and development. Its unique structure allows for various chemical reactions and transformations, making it a valuable component in the creation of new molecules and materials.
Used in Laboratory Applications:
4-Methylamino-3-Nitro-Benzaldehyde is used as a research compound in laboratory settings, where it is employed in the study of chemical reactions and the development of new methodologies. Its potential applications in the synthesis of pharmaceuticals, materials, and other compounds are being explored, with a focus on understanding its reactivity and properties under controlled conditions.

InChI:InChI=1/C8H8N2O3/c1-9-7-3-2-6(5-11)4-8(7)10(12)13/h2-5,9H,1H3

Upstream product

• 662165-72-2 2-(4'-chloro-3'-nitrophenyl)-1,3-oxathiolane 
• 16588-34-4 4-chloro-3-nitro-benzaldehyde 
• 662165-70-0 2-(4'-methylamino-3'-nitrophenyl)-1,3-oxathiolane 
• 74-89-5 methylamine 
• 31680-08-7 4-methoxy-3-nitrobenzaldehyde 
• 96014-61-8 3-nitro-4-methoxybenzylidenemethylamine 
• 96022-30-9 3-nitro-4-chlorobenzylidenemethylamine 

Downstream Products

• 62347-97-1 (4-(methylamino)-3-nitrophenyl)methanol 
• 690265-16-8 methyl-(2-nitro-4-pyrrolidin-1-ylmethyl-phenyl)-amine 
• 138208-26-1 2-<4-(methylamino)-3-nitrobenzyl>-α-cyclodextrin 
• 130597-56-7 4-(chloromethyl)-N-methyl-2-nitrobenzenamine 
• 662165-70-0 2-(4'-methylamino-3'-nitrophenyl)-1,3-oxathiolane 

Relevant articles and documents

Metalloporphyrin and heteropoly acid catalyzed oxidation of C=NOH bonds in an ionic liquid: Biomimetic models of nitric oxide synthase

Water soluble iron(III) porphyrins and phosphotungstic acid in an ionic liquid are effective catalysts for the H2O2 mediated oxidation of the CNOH bond in N-hydroxyarginine and other oximes. The carbonyl compounds generated as the oxidation products can be easily isolated from the reaction media. These systems serve as biomimetic models of nitric oxide synthase (NOS) and the catalyst immobilized in an ionic liquid can be easily recycled and reused.

Deprotection of 1,3-oxathiolanes to carbonyl compounds with montmorillonite K10

Montmorillonite K10 has been used in the deprotection of different aromatic and aliphatic 1,3-oxathiolanes to the corresponding carbonyl compounds in 73 to 97% yields under mild and environmentally compatible conditions.

Artificial Redox Enzymes. 1. Synthetic Strategies

Organic models of flavoenzymes consist of a binding site covalently attached to a flavin derivative acting as the catalytic site.The earlier reported synthesis of such a model using α-cyclodextrin as the binding site proved to be difficult to reproduce wi

ACTIVATING EFFECT OF THE IMINIUM GROUP IN AROMATIC NUCLEOPHILIC SUBSTITUTION OF AN ALKOXY GROUP AND HALOGEN ATOMS BY THE ACTION OF NITROGEN BASES

The characteristics of aromatic nucleophilic substitution with activation by the iminium group in the iminium derivatives of p-alkoxy- and p-halogenobenzaldehydes were investigated.They are determined by the concurrent addition of the nucleophilic agents at the C=N multiple bond.The activating effect of the iminium group depends on the nature of the leaving group, the solvent, the substituent in the benzene ring, and the nature and concentration of the protonating agent.The action of heat on p-methoxybenzylidenemethylamine with a tenfold excess of methylamine hydrochloride in a 30percent alcohol solution of methylamine at 150 deg C for 40 h leads to substitutioon of the methoxymethylamino group with a yield of 90percent.