425663-71-4

Basic information

• Product Name: 2H-3-Benzazepin-2-one, 1-amino-1,3,4,5-tetrahydro-3-methyl-, hydrochloride (1:1), (1S)-
• Synonyms: 2H-3-Benzazepin-2-one, 1-amino-1,3,4,5-tetrahydro-3-methyl-, hydrochloride (1:1), (1S)-;(S)-1-amino-3-methyl-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one hydrochloride;(S)-1-aMino-3-Methyl-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one hyd;S-1-aMino-4,5-dihydro-3-Methyl-1H-benzo[d]azepin-2(3H)-one;2H-3-Benzazepin-2-one, 1-aMino-1,3,4,5-tetrahydro-3-Methyl-, hydrochloride (1:1);-1-Amino-3-methyl-4,5-dihydro-1H-benzo[d]azepin-2(3H);(S)-1-AMINO-3-METHYL-4,5-DIHYDRO-1H-BENZO[D]AZEPIN-2(3H)-ONE HCL
• CAS NO: 425663-71-4
• Molecular Formula: C₁₁H₁₄N₂O*ClH
• Molecular Weight: 226.706
• Mol File: 425663-71-4.mol

Chemical Properties

• Melting Point: >230 °C
• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2H-3-Benzazepin-2-one, 1-amino-1,3,4,5-tetrahydro-3-methyl-, hydrochloride (1:1), (1S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-3-Benzazepin-2-one, 1-amino-1,3,4,5-tetrahydro-3-methyl-, hydrochloride (1:1), (1S)-(425663-71-4)
• EPA Substance Registry System: 2H-3-Benzazepin-2-one, 1-amino-1,3,4,5-tetrahydro-3-methyl-, hydrochloride (1:1), (1S)-(425663-71-4)

Safety Data

• Hazardous Substances Data: 425663-71-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2H-3-Benzazepin-2-one, 1-amino-1,3,4,5-tetrahydro-3-methyl-, hydrochloride (1:1), (1S)is used as a pharmaceutical intermediate for the synthesis of various drugs. Its unique chemical structure and properties make it a promising candidate for the development of new therapeutic agents.
Used in Chemical Research:
In the field of chemical research, 2H-3-Benzazepin-2-one, 1-amino-1,3,4,5-tetrahydro-3-methyl-, hydrochloride (1:1), (1S)serves as a valuable compound for studying the properties and reactivity of benzazepine derivatives. It can be used to explore new synthetic routes, reaction mechanisms, and potential applications in various chemical processes.
Used in Biochemical Studies:
2H-3-Benzazepin-2-one, 1-amino-1,3,4,5-tetrahydro-3-methyl-, hydrochloride (1:1), (1S)may also be employed in biochemical studies to investigate its interactions with biological molecules, such as enzymes, receptors, or other proteins. This can provide insights into its potential role in biological systems and its use as a tool for understanding specific biochemical processes.
Used in Material Science:
In material science, 2H-3-Benzazepin-2-one, 1-amino-1,3,4,5-tetrahydro-3-methyl-, hydrochloride (1:1), (1S)could be explored for its potential use in the development of new materials with unique properties. Its chemical structure may contribute to the creation of novel materials with applications in various industries, such as electronics, coatings, or sensors.

Upstream product

• 13230-84-7 2-chloro-N-methyl-N-(2-phenylethyl)acetamide 
• 103-63-9 1-phenyl-2-bromoethane 
• 589-08-2 N-Methyl-N-phenethylamine 
• 73644-95-8 1,2,4,5-tetrahydro-3-methyl-3H-3-benzazepin-2-one 
• 253324-91-3 1-amino-3-methyl-1H,4H,5H-benzo-[d]azaperhydroepin-2-one 

Downstream Products

• 253324-93-5 C₁₉H₂₇N₃O₄ 
• 1093881-94-7 C₁₉H₂₀N₂O₃ 
• 1093881-95-8 C₁₈H₁₇N₃O₅ 

Relevant articles and documents

METHOD FOR PRODUCING BENZAZEPINONE

It is an object of the present invention to provide 2-iminocarboxylic acid derivatives, and a practically suitable industrial method for producing benzazepinones in a short process under mild conditions. The present invention provides a method for producing a benzazepinone or a salt thereof, which comprises opening a ring of an isoquinoline derivative and subsequently converting the thus generated amine into a benzazepinone through lactamization reaction.

Classical and dynamic resolution of 1-amino-3-methyl-1,3,4,5- tetrahydrobenzo[d]azepin-2-one

Two efficient production processes of enantioenriched 1-amino-3-methyl-1,3, 4,5-tetrahydro-benzo[d]azepin-2-one 1 were achieved using the readily available starting materials. A key step in the methodologies is a classical resolution or a dynamic resolution that provides excellent chemical (>80%) yields and enantiomeric excesses (>99.8% ee). The classical resolution was developed on a preparative scale while the dynamic resolution was implemented on a pilot plant scale.