426830-18-4Relevant articles and documents
THERAPEUTIC COMPOUNDS
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Page/Page column 48-50, (2009/05/30)
The present invention relates to pyrazine substituted pyrrolopyridines which are inhibitors of JAK kinases (JAKl, JAK2, JAK3 and/or TYK2) and/or PDKl and are thus useful for the treatment of myeloproliferative disorders or cancer.
PIPERIDINE DERIVATIVES USEFUL AS HISTAMINE H3 ANTAGONISTS
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Page/Page column 26, (2010/11/25)
Disclosed are novel compounds of the formula (I) or a pharmaceutically acceptable salt thereof, wherein: M1 and M3 are CH or N; M2 is CH, CF or N; Y is -C(=O)-, -C(=S)-, -(CH2)q-, -C(=NOR7)
Peptide compounds
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, (2008/06/13)
The present invention relates to a compound of the formula (I)wherein R1 is benzofuranyl substituted by halogen, or styryl substituted by halogen; R2 is substituted hydroxy, substituted mercapto or substituted sulfonyl; and X is or pharmaceutically acceptable salts thereof. The compound (1) of the present invention and pharmaceutically acceptable salts thereof possess a strong inhibitory activity on the production of nitric oxide (NO), and are useful for prevention and/or treatment of NO-mediated diseases in human being and animals.
Novel compounds and their use
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, (2008/06/13)
A compound of the general formula (I): wherein R1, R2, X, Y and Z are as described in the specification.