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426834-69-7

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426834-69-7 Usage

Biochem/physiol Actions

NS5806 increases peak current amplitude of the potassium channel Kv4.3 (EC50 = 5.3 uM). NS5806 also slows Kv4.3 and Kv4.2 current dacay in channel complexes containing KChIP2. In ventricular cardiomycytes, NS5806 increases transient outward current and reproduces the electrocardiographic profile of Brugada syndrome.

Check Digit Verification of cas no

The CAS Registry Mumber 426834-69-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,2,6,8,3 and 4 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 426834-69:
(8*4)+(7*2)+(6*6)+(5*8)+(4*3)+(3*4)+(2*6)+(1*9)=167
167 % 10 = 7
So 426834-69-7 is a valid CAS Registry Number.

426834-69-7 Well-known Company Product Price

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  • Sigma

  • (N2540)  NS5806  ≥98% (HPLC)

  • 426834-69-7

  • N2540-5MG

  • 1,153.62CNY

  • Detail
  • Sigma

  • (N2540)  NS5806  ≥98% (HPLC)

  • 426834-69-7

  • N2540-25MG

  • 4,687.02CNY

  • Detail

426834-69-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[3,5-bis(trifluoromethyl)phenyl]-3-[2,4-dibromo-6-(2H-tetrazol-5-yl)phenyl]urea

1.2 Other means of identification

Product number -
Other names NS5806

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:426834-69-7 SDS

426834-69-7Downstream Products

426834-69-7Relevant articles and documents

FUNCTION CONTROL AGENT FOR PLANT POTASSIUM ION TRANSPORTER, AND METHOD OF GROWING PLANT

-

, (2019/09/18)

PROBLEM TO BE SOLVED: To provide: a function control agent for a plant potassium ion transporter by screening diphenylurea compound derivatives having function control activity targeting a transporter of a plant; and a method of growing a plant body modif

Effect of the Ito activator NS5806 on cloned Kv4 channels depends on the accessory protein KChIP2

Lundby,Jespersen,Schmitt,Grunnet,Olesen,Cordeiro, Jm,Calloe

body text, p. 2028 - 2044 (2011/05/05)

BACKGROUND AND PURPOSE The compound NS5806 increases the transient outward current (Ito) in canine ventricular cardiomyocytes and slows current decay. In human and canine ventricle, Ito is thought to be mediated by KV4.3 a

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