- COMPOUNDS CONTAINING AN ALICYCLIE STRUCTURE AND ANTI-TUMOR APPLICATION
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This invention relates with anti-tumor activities of new compounds containing an adamantyl group or analogs thereof. The invention also relates with the medication applications of anti-tumor and other diseases by this kind of compounds with the combination of S, P, T structures containing adamantyl group and the formation of stereoisomer, tautomers, prodrug, pharmaceutically acceptable salts, complex salts or solvates to their anticancer application and anticancer agents, which have the following general formula:
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Paragraph 0052
(2014/03/21)
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- Face selection in additions to the trigonal C2 site in quaternized 5-azaadamantane derivatives
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The quaternary N-allyl bromide salt 5 of allyl α-[2-(5-azaadamantylidene)]benzyl ether upon warming gave the Claisen rearrangement products 6 is the ratio E/Z = 93:7. The epoxidation of the N-oxide 8 of 2-methylene-5-azaadamantane 7 with m-CPBA gives rise
- Lau, Jacqueline,Gonikberg, Elena M.,Hung, Jui-Te,Le Noble, William J.
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p. 11421 - 11425
(2007/10/03)
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