42949-24-6

Basic information

• Product Name: 5-Azaadamantan-2-one
• Synonyms: 5-Azaadamantan-2-one;1-Aza-4-oxoadamantane;1-Azaadamantan-4-one;1-Azatricyclo[3.3.1.13,7]decan-4-one;1-Azatricyclo[3.3.1.1(3,7)
• CAS NO: 42949-24-6
• Molecular Formula: C₉H₁₃NO
• Molecular Weight: 151.208
• Mol File: 42949-24-6.mol

Chemical Properties

• Boiling Point: 265 ºC
• Flash Point: 106 ºC
• Appearance: /
• Density: 1.19
• Vapor Pressure: 0.01mmHg at 25°C
• Refractive Index: 1.569
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-Azaadamantan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Azaadamantan-2-one(42949-24-6)
• EPA Substance Registry System: 5-Azaadamantan-2-one(42949-24-6)

Safety Data

• Hazardous Substances Data: 42949-24-6(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
5-Azaadamantan-2-one is utilized as a building block in the synthesis of various organic compounds. Its unique structure and reactivity make it a versatile precursor in chemical reactions, contributing to the creation of a wide array of organic molecules.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 5-Azaadamantan-2-one serves as a valuable compound for the development of pharmaceuticals. The presence of the nitrogen atom in its ring structure allows for functionalization and modification, enhancing its potential as a precursor in the synthesis of novel therapeutic agents.
Used in Pharmaceutical Development:
5-Azaadamantan-2-one is employed as a key intermediate in the design and synthesis of new pharmaceuticals. Its unique structural features and reactivity provide opportunities for the development of innovative drugs with improved efficacy and selectivity.
Used in Chemical Research:
5-Azaadamantan-2-one is also used in chemical research to explore new reaction pathways and mechanisms. Its unique properties make it an interesting subject for studying the effects of nitrogen substitution in cyclic structures and their implications in chemical behavior.
Used in Drug Design and Discovery:
5-Azaadamantan-2-one plays a role in drug design and discovery, where its structural attributes can be leveraged to create molecules with specific biological activities. Its adaptability in chemical reactions facilitates the development of targeted therapeutic agents for various medical conditions.

InChI:InChI=1/C9H13NO/c11-9-7-1-6-2-8(9)5-10(3-6)4-7/h6-8H,1-5H2

Upstream product

• 50-00-0 formaldehyd 
• 30482-25-8 (1,4-dioxa-spiro[4.5]dec-8-yl)-methyl-amine 

Downstream Products

• 1159913-04-8 C₂₁H₂₉ClFN₃ 
• 42949-22-4 1-Aza-adamant-4-methylen 
• 1065011-25-7 1-azatricyclo[3.3.1.1(3,7)]decan-4-one O-(4-chlorophenyl)oxime hydrochloride 
• 1065011-30-4 1-azatricyclo[3.3.1.1(3,7)]decan-4-one O-(pentafluorophenyl-methyl)oxime hydrochloride 
• 281-27-6 1-aza-adamantane 

Relevant articles and documents

MULTICYCLIC TERTIARY AMINE POLYAROMATIC SQUALENE SYNTHASE INHIBITORS

This invention relates to polycyclic compounds containing two mono- and/or bicyclic rings and a basic tertiary amino group capable of forming an ammonium ion at biological pH and which reduces levels of serum cholesterol in the body without significantly reducing mevalonic metabolite synthesis. This invention relates also to pharmacological compositions and method of treatment for lowering serum cholesterol levels using the compounds of this invention. The compounds of this invention are described by the formula where Ar I is phenylene or naphthylene, Ar II is phenyl or naphthyl and A is 1-azabicyclo[2.2.2]octan-3-yl