42951-39-3

Basic information

• Product Name: 1-Octyl-2-methylindole
• Synonyms: 2-METHYL-1-N-OCTYLINDOLE;1-N-OCTYL-2-METHYLINDOLE;1-OCTYL-2-METHYLINDOLE;2-methyl-1-octyl-1h-indol;2-methyl-1-octylindole;2-methyl-1-octyl-1H-indole;n-Octyl-1,2-methylindole;1-Octyl-2-mthylindole
• CAS NO: 42951-39-3
• Molecular Formula: C₁₇H₂₅N
• Molecular Weight: 243.39
• EINECS: 256-016-5
• Product Categories: Heterocycle-Indole series
• Mol File: 42951-39-3.mol

Chemical Properties

• Boiling Point: 367.269 °C at 760 mmHg
• Flash Point: 175.919 °C
• Appearance: /
• Density: 0.942 g/cm³
• Vapor Pressure: 2.92E-05mmHg at 25°C
• Refractive Index: 1.526
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-Octyl-2-methylindole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Octyl-2-methylindole(42951-39-3)
• EPA Substance Registry System: 1-Octyl-2-methylindole(42951-39-3)

Safety Data

• Hazardous Substances Data: 42951-39-3(Hazardous Substances Data)

Usage

Uses

Used in the Food Industry:
1-Octyl-2-methylindole is used as a flavoring agent for enhancing the taste of meats and savory products, providing a unique and desirable flavor profile to these food items.
Used in the Perfume Industry:
1-Octyl-2-methylindole is used as a fragrance ingredient, capitalizing on its strong, musky scent to contribute to the creation of various perfumes and scented products.
Used in Environmental Monitoring:
As a volatile organic compound emitted from automobile exhaust, 1-Octyl-2-methylindole is monitored as a potential air pollutant, helping in the assessment and control of air quality and emissions from vehicles.
It is crucial to handle and use 1-Octyl-2-methylindole with caution due to its potential health and environmental effects, ensuring responsible practices in its application across industries.

InChI:InChI=1/C17H25N/c1-3-4-5-6-7-10-13-18-15(2)14-16-11-8-9-12-17(16)18/h8-9,11-12,14H,3-7,10,13H2,1-2H3

Upstream product

• 111-86-4 n-Octylamine 
• 21906-31-0 1-(2-bromophenyl)propane-2-one 
• 694-80-4 2-bromo-1-chlorobenzene 
• 67-64-1 acetone 
• 615-41-8 2-iodochlorobenzene 

Downstream Products

• 60316-84-9 (2-methyl-1-n-octylindol-3-yl)-(2-carboxyphenyl)ketone 

Relevant articles and documents

Utilizing Mor-DalPhos/palladium-catalyzed monoarylation in the multicomponent one-pot synthesis of indoles

The application of a Mor-DalPhos/palladium catalyst system in the one-pot, multicomponent assembly of substituted indoles from ortho-chlorohaloarenes, alkyl ketones (including acetone), and primary amines is reported. The described protocols offer improved substrate scope in all three reaction components, under more mild conditions and without the need for an additional drying agent. Also reported are the first examples of such multicomponent reactions where all reactants are combined at the start of the reaction, without the need for inert atmosphere reaction conditions.

Indoles synthesized from amines via copper catalysis

N-Substituted indoles are synthesized from primary amines through a tandem reaction sequence. Initial condensation of the amine with an α-(o-haloaryl)ketone or aldehyde is followed by intramolecular aryl amination catalyzed by CuI. A variety of anilines and alkyl amines, including those with significant steric demands, are converted to indoles in high yields and with varying indole substitution.

3,5- And 5,5-bis(3-indolyl)-2-(5H)furanones

Mono-, bis- and tris-indolyl-substituted furanones useful as color formers, particularly in carbonless duplicating and thermal marking systems, which are prepared respectively by: the interaction of an indole with mucochloric acid; the interaction of an indole with a 4-mono(indolyl-substituted 4-oxo-2-butenoic acid; and by the interaction of an indole with a 2,4-bis(indolyl)-substituted 4-oxobutanoic acid or with a 3,5-bis(indolyl)-substituted furanone.

Diphenylamino and indolyl substituted pyromellitides

This invention relates to 3,7-bis(disubstituted aminophenyl- or indolyl)-3,7-bis(diphenylamino)pyromellitides, 3,5-bis(disubstituted aminophenyl- or indolyl)-3,5-bis(diphenylamino)pyromellitides and mixtures thereof useful as color formers, particularly in carbonless duplicating and thermal marking systems, which are prepared by the interaction of 2,5-bis(disubstituted aminophenyl- or indolyl)carbonyl-1,4-benzenedicarboxylic acids or 2,4-bis(disubstituted aminophenyl- or indolyl)carbonyl-1,5-benzenedicarboxylic acids and mixtures thereof with diphenylamines.

Indolyl phthalide compounds

3-Aryl-3-indolylphthalides, 3-aryl-3-pyrrolylphthalides and 3-aryl-3-carbazolylphthalides prepared by interaction of the appropriate 2-(heteroaryl)carbonylbenzoic acid and the appropriate phenylamine, and 3,3-bis(indolyl)phthalides prepared by the interaction of the appropriate 2-(indolyl)carbonylbenzoic acid and the appropriate indole are useful as color formers in pressure-sensitive carbonless duplicating systems, thermal marking systems and hectographic copying systems.

Novel compounds, processes and marking systems

Mono and bis substituted (arylsulfonyl)alkanes useful as color formers, particularly in carbonless duplicating and thermal marking systems, are prepared by the interaction of the appropriate aldehyde or dialdehyde with the appropriate aryl or heterocyclic moiety and the appropriate phenylsulfinic acid in the presence of a catalyst.

Heteroarylphthalides

3-Aryl-3-indolylphthalides, 3-aryl-3-pyrrolylphthalides and 3-aryl-3-carbazolylphthalides prepared by interaction of the appropriate 2-(heteroaryl)carbonylbenzoic acid and the appropriate phenylamine, and 3,3-bis(indolyl)-phthalides prepared by the interaction of the appropriate 2-(indolyl)carbonylbenzoic acid and the appropriate indole are useful as color formers in pressure-sensitive carbonless duplicating systems, thermal marking systems and hectographic copying systems.

Phthalide compounds, processes and marking systems

3-Aryl-3-indolylphthalides, 3-aryl-3-pyrrolylphthalides and 3-aryl-3-carbazolylphthalides prepared by interaction of the appropriate 2-(heteroaryl)carbonylbenzoic acid and the appropriate phenylamine, and 3,3-bis(indolyl)phthalides prepared by the interaction of the appropriate 2-(indolyl)carbonylbenzoic acid and the appropriate indole are useful as color formers in pressure-sensitive carbonless duplicating systems, thermal marking systems and hectographic copying systems.

3,5-Bis (indolyl)-5-(indolyl)-2(5H)-furanones

Mono-, bis- and tris-indolyl-substituted furanones useful as color formers, particularly in carbonless duplicating and thermal marking systems, which are prepared respectively by: the interaction of an indole with mucochloric acid; the interaction of an indole with a 4-mono(indolyl)-substituted 4-oxo-2-butenoic acid; and by the interaction of an indole with a 2,4-bis(indolyl)-substituted 4-oxobutanoic acid or with a 3,5-bis(indolyl)-substituted furanone.