433728-73-5 Usage
Chemical structure
The compound has a benzamide core structure with an amino-pyridinyl group and two isopropyl substituents.
Biological activities
The compound has reported anti-inflammatory and antiproliferative properties.
Potential therapeutic applications
The compound has been studied for its potential in treating various diseases, including cancer and inflammatory conditions.
Ongoing research
Further research is being conducted on the pharmacological properties and potential therapeutic applications of the compound.
Check Digit Verification of cas no
The CAS Registry Mumber 433728-73-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,3,3,7,2 and 8 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 433728-73:
(8*4)+(7*3)+(6*3)+(5*7)+(4*2)+(3*8)+(2*7)+(1*3)=155
155 % 10 = 5
So 433728-73-5 is a valid CAS Registry Number.
InChI:InChI=1/C18H23N3O/c1-12(2)21(13(3)4)18(22)15-8-6-5-7-14(15)16-11-20-10-9-17(16)19/h5-13H,1-4H3,(H2,19,20)
433728-73-5Relevant articles and documents
Compounds and their use
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, (2008/06/13)
This invention relates to compounds, pharmaceutical compositions, and methods of using the disclosed compounds for inhibiting PARP.
Design and synthesis of poly ADP-ribose polymerase-1 inhibitors. 2. Biological evaluation of aza-5[H]-phenanthridin-6-ones as potent, aqueous-soluble compounds for the treatment of ischemic injuries
Ferraris, Dana,Ko, Yao-Sen,Pahutski, Thomas,Ficco, Rica Pargas,Serdyuk, Larisa,Alemu, Christina,Bradford, Chadwick,Chiou, Tiffany,Hoover, Randall,Huang, Shirley,Lautar, Susan,Liang, Shi,Lin, Qian,Lu, May X.-C.,Mooney, Maria,Morgan, Lisa,Qian, Yongzhen,Tran, Scott,Williams, Lawrence R.,Wu, Qi Yi,Zhang, Jie,Zou, Yinong,Kalish, Vincent
, p. 3138 - 3151 (2007/10/03)
A series of aza-5[H]-phenanthridin-6-ones were synthesized and evaluated as inhibitors of poly ADP-ribose polymerase-1 (PARP-1). Inhibitory potency of the unsubstituted aza-5[H]-phenanthridin-6-ones (i.e., benzonaphthyridones) was dependent on the positio