88511-27-7

Basic information

• Product Name: 3-Iodo-4-aminopyridine
• Synonyms: 3-IODO-4-AMINOPYRIDINE;3-IODO-PYRIDIN-4-YLAMINE;4-AMINO-3-IODOPYRIDINE;3-Iodopyridin-4-amine;3-Iodo-4-aminopyridi;4-AMino-3-iodopyridine 98%;4-AMino-3-iodopyridine, 97+%
• CAS NO: 88511-27-7
• Molecular Formula: C₅H₅IN₂
• Molecular Weight: 220.01
• EINECS: -0
• Product Categories: pharmacetical;Pyridine;Building Blocks;C5;Chemical Synthesis;Heterocyclic Building Blocks;New Products for Chemical Synthesis;Pyridines
• Mol File: 88511-27-7.mol
• Article Data: 23

Chemical Properties

• Melting Point: 99.1-99.4°C
• Boiling Point: 335.1 °C at 760 mmHg
• Flash Point: 156.4 °C
• Appearance: /
• Density: 2.055 g/cm³
• Vapor Pressure: 0.000123mmHg at 25°C
• Refractive Index: 1.702
• Storage Temp.: 2-8°C
• Solubility: soluble in Methanol
• PKA: 7.34±0.12(Predicted)
• Sensitive: Light Sensitive
• CAS DataBase Reference: 3-Iodo-4-aminopyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Iodo-4-aminopyridine(88511-27-7)
• EPA Substance Registry System: 3-Iodo-4-aminopyridine(88511-27-7)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22-37/38-41
• Safety Statements: 26-39
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 88511-27-7(Hazardous Substances Data)

Usage

Chemical Properties

Off-white solid

InChI:InChI=1/C5H5IN2/c6-4-3-8-2-1-5(4)7/h1-3H,(H2,7,8)

Upstream product

• 13534-98-0 3-bromopyridin-4-amine 
• 70298-89-4 4-N-pivaloylaminopyridine 
• 113975-33-0 2,2-dimethyl-N-(3-iodo-4-pyridinyl)propanamide 
• 504-24-5 4-aminopyridine 

Downstream Products

• 253-72-5 1,6-naphthyridine 
• 351227-37-7 3-[2-(4-chloro-phenyl)-1H-pyrrolo[3,2-c]pyridin-3-yl]-propionic acid methyl ester 
• 433728-73-5 2-(4-aminopyridin-3-yl)-N,N-diisopropylbenzamide 
• 52816-59-8 2-phenyl-[1,6]naphthyridine 
• 53439-83-1 benzo[c][1,6]naphthyridin-6(5H)-one 
• 1377578-85-2 2-phenyl-3-(pyridin-4-yl)-1H-pyrrolo[3,2-c]pyridine 
• 1377578-65-8 3-phenyl-2-(pyridin-4-yl)-1H-pyrrolo[3,2-c]pyridine 
• 1377578-68-1 2-methyl-3-phenyl-1H-pyrrolo[3,2-c]pyridine 
• 263902-21-2 3-methyl-2-phenyl-1H-pyrrolo[3,2-c]pyridine 
• 1377578-69-2 2-butyl-3-phenyl-1H-pyrrolo[3,2-c]pyridine 
• 1377578-86-3 3-butyl-2-phenyl-1H-pyrrolo[3,2-c]pyridine 
• 1377578-70-5 2-(methoxymethyl)-3-phenyl-1H-pyrrolo[3,2-c]pyridine 
• 1377578-87-4 3-(methoxymethyl)-2-phenyl-1H-pyrrolo[3,2-c]pyridine 
• 1377578-71-6 2-isobutyl-3-phenyl-1H-pyrrolo[3,2-c]pyridine 

Relevant articles and documents

Process Optimization for the Large-Scale Preparation of (2 S,3 aR,7 aS)- tert-Butyl Hexahydro-2,5-methanopyrrolo[3,2- c]pyridine-1(4 H)-carboxylate, an Intermediate for Nicotinic Acetylcholine Receptor Agonists

An optimized large-scale synthesis of (2S,3aR,7aS)-tert-butyl hexahydro-2,5-methanopyrrolo[3,2-c]pyridine-1(4H)-carboxylate (1A), an important intermediate for nicotinic acetylcholine receptor agonists, is described. The key feature of the synthesis involves three transformations in a one-pot process, including debenzylation and ring hydrogenation of two fused bicyclic rings. Multihundred gram quantities of 1A were prepared.

AMIDO-BENZYL SULFONE AND SULFOXIDE DERIVATIVES

The present invention relates to certain amido-benzyl sulfoxide and sulfone compounds, pharmaceutical compositions comprising such compounds, and methods of treatment using such compounds.

AMIDO SPIROCYCLIC AMIDE AND SULFONAMIDE DERIVATIVES

Provided are amido spirocyclic amide and sulfonamide compounds, pharmaceutical compositions comprising such compounds, and methods of treatment using such compounds.