434941-56-7

Basic information

• Product Name: 4-(4-Chlorophenyl)-2-(Methylsulfonyl)pyriMidine
• Synonyms: 4-(4-Chlorophenyl)-2-(Methylsulfonyl)pyriMidine
• CAS NO: 434941-56-7
• Molecular Formula: C₁₁H₉ClN₂O₂S
• Molecular Weight: 268.71936
• Mol File: 434941-56-7.mol

Chemical Properties

• Boiling Point: 479.372 °C at 760 mmHg
• Flash Point: 243.716 °C
• Appearance: /
• Density: 1.379 g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-(4-Chlorophenyl)-2-(Methylsulfonyl)pyriMidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-Chlorophenyl)-2-(Methylsulfonyl)pyriMidine(434941-56-7)
• EPA Substance Registry System: 4-(4-Chlorophenyl)-2-(Methylsulfonyl)pyriMidine(434941-56-7)

Safety Data

• Hazardous Substances Data: 434941-56-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research and Development:
4-(4-Chlorophenyl)-2-(Methylsulfonyl)pyriMidine is used as a reference standard for analytical testing and quality control in the production of pharmaceuticals. Its role in ensuring the purity and efficacy of pharmaceutical products is crucial for maintaining the safety and effectiveness of medications.
Used in Synthesis of Related Compounds:
As a starting material, 4-(4-Chlorophenyl)-2-(Methylsulfonyl)pyriMidine is used in the synthesis of other related compounds, contributing to the development of new pharmaceuticals and therapeutic agents.
Used in Biological Research:
4-(4-Chlorophenyl)-2-(Methylsulfonyl)pyriMidine is utilized in biological research to study the effects of pyrimidine derivatives on biological systems. Its unique structure and properties provide insights into the potential therapeutic applications of these compounds, aiding in the discovery of new treatments and therapies.

Upstream product

• 1679-18-1 4-Chlorophenylboronic acid 
• 49844-90-8 4-Chloro-2-methylthiopyrimidine 

Downstream Products

• 1609659-16-6 C₁₇H₁₄ClN₃O 
• 637352-80-8 ethyl [4-({butyl[4-(4-chlorophenyl)pyrimidin-2-yl]amino}methyl)-2-methylphenoxy]acetate 

Relevant articles and documents

NOVEL AMINOMETHYL-PHENOL DERIVATIVES AS ANTIMALARIAL AGENTS

The invention relates to novel aminomethyl-phenol derivatives of formula I wherein R1 to R4, X, A and B are as defined for formula I and their use as active ingredients in the preparation of pharmaceutical compositions. The invention

CHEMICAL COMPOUNDS

A compound of formula (I) or a pharmaceutically acceptable salt, solvate, or hydrolysable ester thereof, .Wherein:R1 and R2 are independently hydrogen or C1-3 alkyl;X represents a bond, CH2 or O;R3 and R4 are independently hydrogen, C1-6 alkyl, OCH3, CF3, allyl or halogen;X1 is CH2, SO2, or CO;R5 is -C1-6 alkyl (optionally substituted by C1-6alkoxy or C1-6alkylthio), -C2-6 alkenyl, -C0-6 alkyl phenyl (wherein the phenyl is optionally substituted by one or more CF3, halogen, C1-3 alkyl, C1-3 alkoxy), -COC1-6 alkyl, SO2C1-6 alkyl ;R6 is phenyl or a 6 membered heteroaryl group containing 1,2 or 3 N atoms wherein the phenyl or heteroaryl group is optionally substituted with 1, 2 or 3 moieties selected from the group consisting of C1-6 alkyl, halogen, -OC1-6 alkyl, -SO2C1-3 alkyl, phenyl (optionally substituted by one or more groups selected from halogen, CF3, C1-3 alkyl, OC1-3 alkyl, acetyl, CN).