436088-80-1

Basic information

• Product Name: (3,4-DIMETHOXY-PHENYL)-FURAN-2-YLMETHYL-AMINE
• Synonyms: (3,4-DIMETHOXY-PHENYL)-FURAN-2-YLMETHYL-AMINE
• CAS NO: 436088-80-1
• Molecular Formula: C₁₃H₁₅NO₃
• Molecular Weight: 233.26
• Mol File: 436088-80-1.mol

Chemical Properties

• Boiling Point: 353.6 °C at 760 mmHg
• Flash Point: 167.6 °C
• Appearance: /
• Density: 1.164 g/cm³
• Vapor Pressure: 3.55E-05mmHg at 25°C
• Refractive Index: 1.572
• Storage Temp.: 2-8°C
• PKA: 4.32±0.50(Predicted)
• CAS DataBase Reference: (3,4-DIMETHOXY-PHENYL)-FURAN-2-YLMETHYL-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: (3,4-DIMETHOXY-PHENYL)-FURAN-2-YLMETHYL-AMINE(436088-80-1)
• EPA Substance Registry System: (3,4-DIMETHOXY-PHENYL)-FURAN-2-YLMETHYL-AMINE(436088-80-1)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 436088-80-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(3,4-DIMETHOXY-PHENYL)-FURAN-2-YLMETHYL-AMINE is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with potential therapeutic benefits.
Used in Agrochemical Industry:
(3,4-DIMETHOXY-PHENYL)-FURAN-2-YLMETHYL-AMINE is utilized as a building block in the creation of agrochemicals, playing a role in the formulation of products designed to protect crops and enhance agricultural yields.
Used in Medical Research:
(3,4-DIMETHOXY-PHENYL)-FURAN-2-YLMETHYL-AMINE is employed as a subject of study in medical research for its neuroprotective and anti-inflammatory properties, which may lead to the discovery of new treatments for neurological disorders.
Used in Oncology Research:
(3,4-DIMETHOXY-PHENYL)-FURAN-2-YLMETHYL-AMINE is used as a compound of interest in oncology research, where it is being investigated for its potential role in the treatment of various types of cancer, possibly through its interaction with cellular mechanisms that could inhibit tumor growth or promote cell death in cancerous cells.

InChI:InChI=1/C13H15NO3/c1-15-12-6-5-10(8-13(12)16-2)14-9-11-4-3-7-17-11/h3-8,14H,9H2,1-2H3

Upstream product

• 98-00-0 (2-furyl)methyl alcohol 
• 6315-89-5 3,4-dimethoxyaniline 

Relevant articles and documents

Synchronizing steric and electronic effects in {RuII(NNNN,P)} complexes: The catalytic dehydrative alkylation of anilines by using alcohols as a case study

A series of new hexacoordinated {RuII(NNNN,P)} complexes was prepared from [RuCl2(R3P)3]. Their structure was determined by X-ray crystallography. The catalytic potential of this new class of complexes was tested in the alkylation of aniline with benzyl alcohol. In this test reaction, the influence of the counteranion plus electronic influences at the tetradentate ligand and the phosphine ligand were examined. The electrochemistry of all complexes was studied by cyclic voltammetry. Depending on the substituent at the ligand backbone, the complexes showed a different behavior. For all N-benzyl substituted complexes, reversible Ru II/III redox potentials were observed, whereas the N-methyl substituted complex possessed an irreversible oxidation event at small scan rates. Furthermore, the electronic influence of different substituents at the ligand scaffold and at the phosphine on the RuII/III redox potential was investigated. The measured E0 values were correlated to the theoretically determined HOMO energies of the complexes. In addition, these HOMO energies correlated well with the reactivity of the single complexes in the alkylation of aniline with benzyl alcohol. The exact balance of redox potential and reactivity appears to be crucial for synchronizing the multiple hydrogen-transfer events. The optimized catalyst structure was applied in a screening on scope and limitation in the catalytic dehydrative alkylation of anilines by using alcohols.