440102-32-9 Usage
Uses
Used in Organic Synthesis and Chemical Research:
2-(3-cyano-pyridin-2-ylamino)ethanol is utilized as a reagent in organic synthesis, playing a crucial role in the formation of complex organic molecules. Its unique structure allows it to participate in a variety of chemical reactions, making it a valuable tool for researchers in the field of chemistry.
Used in Pharmaceutical Development:
2-(3-cyano-pyridin-2-ylamino)ethanol's capacity to bind and inhibit certain enzymes positions it as a potential drug target. This property is particularly significant in the development of new pharmaceuticals, where it may contribute to the creation of treatments for various diseases by interfering with the activity of disease-causing enzymes.
Used in Anti-inflammatory and Antioxidant Applications:
2-(3-cyano-pyridin-2-ylamino)ethanol has been studied for its potential biological activities, including its anti-inflammatory and antioxidant properties. These characteristics suggest that the compound could be used in the development of therapeutic agents aimed at reducing inflammation and oxidative stress, which are common factors in many diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 440102-32-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,0,1,0 and 2 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 440102-32:
(8*4)+(7*4)+(6*0)+(5*1)+(4*0)+(3*2)+(2*3)+(1*2)=79
79 % 10 = 9
So 440102-32-9 is a valid CAS Registry Number.
440102-32-9Relevant articles and documents
Substituted conformationally restricted guanidine derivatives: Probing the α2-adrenoceptors’ binding pocket
McMullan, Michela,García-Bea, Aintzane,Miranda-Azpiazu, Patricia,Callado, Luis F.,Rozas, Isabel
supporting information, p. 48 - 57 (2016/08/01)
In this paper we report the design, synthesis and pharmacological evaluation of new N-substituted 2-amino-1,4-dihydroquinazolines, 2-amino-1,4-dihydropyridopyrimidines and 2-amino-4,5-dihydro-1,3-benzodiazepines as α2-adrenoceptors ligands. Computational studies show that the proposed substitutions and guanidine-containing ring size will probe an extensive area of the active site. Preparation of these molecules involved novel routes than those previously utilised in our laboratory for the preparation of the acyclic aryl-guanidine counterparts. Compounds 8b and 18c showed the highest affinity and antagonistic activity, within their series, towards the α2-adrenoceptor in human brain tissue in?vitro experiments. Structure-activity relationships have been established for the design and biological evaluation of novel α2-adrenoceptor ligands.
DIPEPTIDYL PEPTIDASE IV INHIBITOR
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Page/Page column 65, (2010/11/29)
A compound represented by general formula (I):A-B-D whereinA represents a substituted or unsubstituted 1-pyrrolidinyl group, a substituted or unsubstituted 3-thiazolidinyl group, a substituted or unsubstituted 1-oxo-3-thiazolidinyl group, or the like;B r
