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CAS

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446276-24-0

5-(3-CHLOROPHENOXY)-1,3-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 446276-24-0 Structure

  • Basic information

    1. Product Name: 5-(3-CHLOROPHENOXY)-1,3-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID
    2. Synonyms: 5-(3-CHLOROPHENOXY)-1,3-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID
    3. CAS NO:446276-24-0
    4. Molecular Formula: C12H11ClN2O3
    5. Molecular Weight: 266.68
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 446276-24-0.mol

  • Chemical Properties

    1. Melting Point: 189-191°C
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 5-(3-CHLOROPHENOXY)-1,3-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID(CAS DataBase Reference)
    10. NIST Chemistry Reference: 5-(3-CHLOROPHENOXY)-1,3-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID(446276-24-0)
    11. EPA Substance Registry System: 5-(3-CHLOROPHENOXY)-1,3-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID(446276-24-0)

  • Safety Data

    1. Hazard Codes: Xn
    2. Statements: 22
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 446276-24-0(Hazardous Substances Data)

446276-24-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 446276-24-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,6,2,7 and 6 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 446276-24:
(8*4)+(7*4)+(6*6)+(5*2)+(4*7)+(3*6)+(2*2)+(1*4)=160
160 % 10 = 0
So 446276-24-0 is a valid CAS Registry Number.

446276-24-0Downstream Products

446276-24-0Relevant articles and documents

Discovery of 5-phenoxy-1,3-dimethyl-1H-pyrazole-4-carboxamides as potent agonists of TGR5 via sequential combinatorial libraries

Londregan, Allyn T.,Piotrowski, David W.,Futatsugi, Kentaro,Warmus, Joseph S.,Boehm, Markus,Carpino, Philip A.,Chin, Janice E.,Janssen, Ann M.,Roush, Nicole S.,Buxton, Joanne,Hinchey, Terri

, p. 1407 - 1411 (2013/03/14)

Optimization of a high-throughput screening hit led to the discovery of a new series of 5-phenoxy-1,3-dimethyl-1H-pyrazole-4-carboxamides as highly potent agonists of TGR5. This novel chemotype was rapidly developed through iterative combinatorial library synthesis. It was determined that in vitro agonist potency correlated with functional activity data from human peripheral blood monocytes.

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