453565-86-1

Basic information

• Product Name: Benzoic acid, 3-cyano-5-ethoxy-, methyl ester (9CI)
• Synonyms: Benzoic acid, 3-cyano-5-ethoxy-, methyl ester (9CI);methyl 3-cyano-5-ethoxybenzoate
• CAS NO: 453565-86-1
• Molecular Formula: C₁₁H₁₁NO₃
• Molecular Weight: 205.20994
• Product Categories: ETHOXY
• Mol File: 453565-86-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzoic acid, 3-cyano-5-ethoxy-, methyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 3-cyano-5-ethoxy-, methyl ester (9CI)(453565-86-1)
• EPA Substance Registry System: Benzoic acid, 3-cyano-5-ethoxy-, methyl ester (9CI)(453565-86-1)

Safety Data

• Hazardous Substances Data: 453565-86-1(Hazardous Substances Data)

Upstream product

• 453565-76-9 methyl 3-cyano-5-hydroxy-benzoate 
• 75-03-6 ethyl iodide 
• 1041204-76-5 methyl 3-ethoxy-5-trifluoromethanesulfonyloxybenzoate 
• 557-21-1 dicyanozinc 

Downstream Products

• 1041204-79-8 methyl 3-ethoxy-5-(tetrazol-5-yl)benzoate 

Relevant articles and documents

SPIROCHROMANON DERIVATIVES

The invention relates to a compound of a general formula (I): wherein Ar1 represents a group formed from an aromatic ring selected from a group consisting of benzene, pyrazole, isoxazole, pyridine, indole, 1H-indazole, 1H-furo[2,3-c]pyrazole, 1H-thieno[2,3-c]pyrazole, benzimidazole, 1,2-benzisoxazole, imidazo[1,2-a]pyridine, imidazo[1,5-a]pyridine and 1H-pyrazolo[3,4-b]pyridine, having Ar2, and optionally having one or two or more substituents selected from R3; R1 and R2 each independently represent a hydrogen atom, a halogen atom, a cyano group, a C2-C6 alkenyl group, a C1-C6 alkoxy group, a C2-C7 alkanoyl group, a C2-C7 alkoxycarbonyl group, an aralkyloxycarbonyl group, a carbamoyl-C1-C6 alkoxy group, a carboxy-C2-C6 alkenyl group, or a group of -Q1-N(Ra)-Q2-Rb; or a C1-C6 alkyl group optionally having a substituent; or an aryl or heterocyclic group optionally having a substituent; or a C1-C6 alkyl group or a C2-C6 alkenyl group having the aryl or heterocyclic group; T and U each independently represent a nitrogen atom or a methine group; and V represents an oxygen atom or a sulfur atom. The compound of the invention is useful as therapeutical agents for various ACC-related diseases.

Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists

The present invention provides compounds and pharmaceutical compositions that act as antagonists at metabotropic glutamate receptors, and that are useful for treating neurological diseases and disorders. Methods of preparing the compounds also are disclosed.