Substituted 2-phenyl-4-quinolone-3-carboxylic acid compounds and their use as antitumor agents
Substituted 2-phenyl-4-quinolone-3-carboxylic acid derivatives and their salts were synthesized. The results of preliminary screening revealed that these compounds are potent in killing solid tumor cancers.
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(2008/06/13)
Synthesis and biological relationships of 3′,6-substituted 2-phenyl-4-quinolone-3-carboxylic acid derivatives as antimitotic agents
As part of a continuing search for potential anticancer drug candidates in the 2-phenyl-4-quinolone series, 3′,6-substituted 2-phenyl-4-quinolone-3- carboxylic acid derivatives and their salts were synthesized and evaluated. Preliminary screening showed t