SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF
Disclosed are compounds having potency in the modulation of NMDA receptor activity. Such compounds can be used in the treatment of conditions such as depression and related disorders as well as other disorders.
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Page/Page column 27-28
(2019/08/26)
N-heterocyclic carbene-catalyzed Ireland-Coates claisen rearrangement: Synthesis of functionalized β-lactones
The N-heterocyclic carbene (NHC)-catalyzed Claisen rearrangement of hybrid Ireland-Coates structures has been achieved, allowing the stereoselective synthesis of highly functionalized β-lactones. The reaction proceeds with high diastereoselectivity (>20:1
Candish, Lisa,Lupton, David W.
supporting information
p. 58 - 61
(2013/02/25)
Process for the preparation of gabapentin
A simple, efficient, environmentally improved and economical process for preparing gabapentin, involving enamine alkylation as the key step is disclosed.
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Page/Page column 3
(2008/06/13)
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