460711-33-5Relevant academic research and scientific papers
SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF
-
Page/Page column 27-28, (2019/08/26)
Disclosed are compounds having potency in the modulation of NMDA receptor activity. Such compounds can be used in the treatment of conditions such as depression and related disorders as well as other disorders.
N-heterocyclic carbene-catalyzed Ireland-Coates claisen rearrangement: Synthesis of functionalized β-lactones
Candish, Lisa,Lupton, David W.
supporting information, p. 58 - 61 (2013/02/25)
The N-heterocyclic carbene (NHC)-catalyzed Claisen rearrangement of hybrid Ireland-Coates structures has been achieved, allowing the stereoselective synthesis of highly functionalized β-lactones. The reaction proceeds with high diastereoselectivity (>20:1
Process for the preparation of gabapentin
-
Page/Page column 3, (2008/06/13)
A simple, efficient, environmentally improved and economical process for preparing gabapentin, involving enamine alkylation as the key step is disclosed.
