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Lu AE 58054 Hydrochloride is an investigational drug developed by H. Lundbeck A/S, characterized as a selective, potent, and reversible 5-HT6 receptor antagonist. It has been designed for the treatment of Alzheimer's disease and schizophrenia, with a mechanism of action that involves blocking the 5-HT6 receptor to regulate the release of neurotransmitters such as dopamine and acetylcholine in the brain. Lu AE 58054 Hydrochloride has shown promise in improving cognitive function through preclinical and clinical studies.

467458-02-2

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467458-02-2 Usage

Uses

Used in Pharmaceutical Industry:
Lu AE 58054 Hydrochloride is used as a therapeutic agent for the treatment of neurodegenerative disorders such as Alzheimer's disease. It is employed for its potential to improve cognitive function by modulating the activity of the 5-HT6 receptor, which is implicated in the regulation of neurotransmitter release.
Used in Psychiatric Disorders Treatment:
In the psychiatric field, Lu AE 58054 Hydrochloride is utilized as a treatment for schizophrenia. Its antagonistic effect on the 5-HT6 receptor may contribute to the amelioration of symptoms associated with this psychiatric condition.
Used in Clinical Research:
Lu AE 58054 Hydrochloride is used as a subject of investigation in clinical trials to assess its safety and efficacy. These trials are crucial for determining the drug's potential role in treating the specified disorders and for understanding its impact on human health.
Used in Drug Development:
As an investigational drug, Lu AE 58054 Hydrochloride is used in the development of new pharmaceuticals targeting the 5-HT6 receptor. Its study aids in the advancement of drug discovery and the creation of novel treatments for cognitive and psychiatric conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 467458-02-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,6,7,4,5 and 8 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 467458-02:
(8*4)+(7*6)+(6*7)+(5*4)+(4*5)+(3*8)+(2*0)+(1*2)=182
182 % 10 = 2
So 467458-02-2 is a valid CAS Registry Number.

467458-02-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(6-fluoro-1H-indol-3-yl)-N-[[3-(2,2,3,3-tetrafluoropropoxy)phenyl]methyl]ethanamine,hydrochloride

1.2 Other means of identification

Product number -
Other names CS-1359

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:467458-02-2 SDS

467458-02-2Downstream Products

467458-02-2Relevant articles and documents

Lu AE58054 novel crystal form and preparation method thereof

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Paragraph 0070-0072, (2019/10/23)

The invention relates to a Lu AE58054 novel crystal form and a preparation method and application thereof. Compared with known Lu AE58054, the Lu AE58054 novel crystal form is advantageous in crystallinity, moisture adsorption, shape, appearance and the l

Process for the Manufacture of Idalopirdine via Hydrogenation of an Imine

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Paragraph 0107; 0128, (2017/10/27)

The present invention relates to the preparation of N-(2-(6-fluoro-1H-indol-3-yl)-ethyl)-3-(2,2,3,3-tetrafluoropropoxy)-benzylamine (Compound I), INN-name idalopirdine, and pharmaceutically acceptable salts thereof:

PROCESS FOR THE MANUFACTURE OF IDALOPIRDINE

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Paragraph 0102-0106, (2016/07/05)

Disclosed herein is a process for the preparation of idalopirdine and pharmaceutically acceptable salts thereof.

PROCESSES FOR THE MANUFACTURE OF A PHARMACEUTICALLY ACTIVE AGENT

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Page/Page column 6-7, (2011/07/06)

Disclosed herein are processes for the preparation of a pharmaceutically active agent and pharmaceutically acceptable salts thereof.

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