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473538-02-2

5-(3-BROMOPHENYL)-3-ISOXAZOLECARBOXYLIC ACID ETHYL ESTER is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 473538-02-2 Structure

  • Basic information

    1. Product Name: 5-(3-BROMOPHENYL)-3-ISOXAZOLECARBOXYLIC ACID ETHYL ESTER
    2. Synonyms: 5-(3-BROMOPHENYL)-3-ISOXAZOLECARBOXYLIC ACID ETHYL ESTER
    3. CAS NO:473538-02-2
    4. Molecular Formula: C12H10BrNO3
    5. Molecular Weight: 296.12
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 473538-02-2.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 5-(3-BROMOPHENYL)-3-ISOXAZOLECARBOXYLIC ACID ETHYL ESTER(CAS DataBase Reference)
    10. NIST Chemistry Reference: 5-(3-BROMOPHENYL)-3-ISOXAZOLECARBOXYLIC ACID ETHYL ESTER(473538-02-2)
    11. EPA Substance Registry System: 5-(3-BROMOPHENYL)-3-ISOXAZOLECARBOXYLIC ACID ETHYL ESTER(473538-02-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 473538-02-2(Hazardous Substances Data)

473538-02-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 473538-02-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,3,5,3 and 8 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 473538-02:
(8*4)+(7*7)+(6*3)+(5*5)+(4*3)+(3*8)+(2*0)+(1*2)=162
162 % 10 = 2
So 473538-02-2 is a valid CAS Registry Number.

473538-02-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 5-(3-bromophenyl)-1,2-oxazole-3-carboxylate

1.2 Other means of identification

Product number -
Other names 5-(3-BROMOPHENYL)-3-ISOXAZOLECARBOXYLIC ACID ETHYL ESTER

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:473538-02-2 SDS

473538-02-2Relevant articles and documents

Design, synthesis and biological evaluation of isoxazole-containing biphenyl derivatives as small-molecule inhibitors targeting the programmed cell death-1/ programmed cell death-ligand 1 immune checkpoint

Zhu, Peiyu,Zhang, Jian,Yang, Yifei,Wang, Lixun,Zhou, Jinpei,Zhang, Huibin

, p. 245 - 264 (2021/04/05)

Monoclonal antibodies targeting the programmed cell death-1/ programmed cell death-ligand 1 (PD-1/PD-L1) immune checkpoint have achieved enormous success in cancer immunotherapy. But the antibody-based immunotherapies carry a number of unavoidable deficie

Heterocyclic substituted biphenyl compound as well as preparation method and application thereof

-

, (2021/08/28)

The invention discloses a heterocyclic substituted biphenyl compound as well as a preparation method and application thereof. According to the present invention, the compound can block the PD-1/PD-L1 signal pathway, and can be used as the immune checkpoint PD-1/PD-L1 small molecule inhibitor; and according to the compound disclosed by the invention, the metabolic stability is improved while the high binding rate with PD-L1 protein is maintained. A hydrophilic group is introduced to a heterocyclic ring, and the PD-1/PD-L1 inhibitory activity is improved.

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