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7-Quinolinecarboxylicacid,2-methyl-(9CI) is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 475098-86-3 Structure
  • Basic information

    1. Product Name: 7-Quinolinecarboxylicacid,2-methyl-(9CI)
    2. Synonyms: 7-Quinolinecarboxylicacid,2-methyl-(9CI)
    3. CAS NO:475098-86-3
    4. Molecular Formula: C11H9NO2
    5. Molecular Weight: 187.197
    6. EINECS: N/A
    7. Product Categories: QUINOLINE
    8. Mol File: 475098-86-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 7-Quinolinecarboxylicacid,2-methyl-(9CI)(CAS DataBase Reference)
    10. NIST Chemistry Reference: 7-Quinolinecarboxylicacid,2-methyl-(9CI)(475098-86-3)
    11. EPA Substance Registry System: 7-Quinolinecarboxylicacid,2-methyl-(9CI)(475098-86-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 475098-86-3(Hazardous Substances Data)

475098-86-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 475098-86-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,5,0,9 and 8 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 475098-86:
(8*4)+(7*7)+(6*5)+(5*0)+(4*9)+(3*8)+(2*8)+(1*6)=193
193 % 10 = 3
So 475098-86-3 is a valid CAS Registry Number.

475098-86-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name quinaldine-7-carboxylic acid

1.2 Other means of identification

Product number -
Other names 2-Methyl-quinoline-7-carboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:475098-86-3 SDS

475098-86-3Downstream Products

475098-86-3Relevant articles and documents

Investigating the antiproliferative activity of quinoline-5,8-diones and styrylquinolinecarboxylic acids on tumor cell lines

Podeszwa,Niedbala,Polanski,Musiol,Tabak,Finster,Serafin,Milczarek,Wietrzyk,Boryczka,Mol,Jampilek,Dohnal,Kalinowski,Richardson

, p. 6138 - 6141 (2007)

The structure-activity relationships of new quinoline based compounds were investigated. Quinoline-5,8-dione and styrylquinoline scaffolds were used for the design of potentially active compounds. The novel analogues had comparable antiproliferative activ

Quinoline-galactose hybrids bind selectively with high affinity to a galectin-8 N-terminal domain

Pal, Kumar Bhaskar,Mahanti, Mukul,Huang, Xiaoli,Persson, Stella,Sundin, Anders P.,Zetterberg, Fredrik R.,Oredsson, Stina,Leffler, Hakon,Nilsson, Ulf J.

, p. 6295 - 6305 (2018/09/10)

Quinolines, indolizines, and coumarins are well known structural elements in many biologically active molecules. In this report, we have developed straightforward methods to incorporate quinoline, indolizine, and coumarin structures into galactoside derivatives under robust reaction conditions for the discovery of glycomimetic inhibitors of the galectin family of proteins that are involved in immunological and tumor-promoting biological processes. Evaluation of the quinoline, indolizine and coumarin-derivatised galactosides as inhibitors of the human galectin-1, 2, 3, 4N (N-terminal domain), 4C (C-terminal domain), 7, 8N, 8C, 9N, and 9C revealed quinoline derivatives that selectively bound galectin-8N, a galectin with key roles in lymphangiogenesis, tumor progression, and autophagy, with up to nearly 60-fold affinity improvements relative to methyl β-d-galactopyranoside. Molecular dynamics simulations proposed an interaction mode in which Arg59 had moved 2.5 ? and in which an inhibitor carboxylate and quinoline nitrogen formed structure-stabilizing water-mediated hydrogen bonds. The compounds were demonstrated to be non-toxic in an MTT assay with several breast cancer cell lines and one normal cell line. The improved affinity, selectivity, and low cytotoxicity suggest that the quinoline-galactoside derivatives provide an attractive starting point for the development of galectin-8N inhibitors potentially interfering with pathological lymphangiogenesis, autophagy, and tumor progression.

TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS

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Page/Page column 88, (2012/12/13)

Compounds of Formula I: in which R1, R2, R3, R4 and R10 have the meanings given in the specification, are receptor tyrosine inhibitors useful in the treatment of diseases mediated by PIM-1 and/or PIM-2 and/or PIM-3 kinases.

Use of the Kohonen neural network for rapid screening of ex vivo anti-HIV activity of styrylquinolines

Polanski, Jaroslaw,Zouhiri, Fatima,Jeanson, Laurence,Desma?le, Didier,D'Angelo, Jean,Mouscadet, Jean-Fran?ois,Gieleciak, Rafal,Gasteiger, Johann,Le Bret, Marc

, p. 4647 - 4654 (2007/10/03)

Using the Kohonen neural network, the electrostatic potentials on the molecular surfaces of 14 styrylquinoline derivatives were drawn as comparative two-dimensional maps and compared with their known human immunodeficiency virus (HIV)-1 replication blocki

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