- [(6 - Substituted - pyrimidine -4 - oxyacetyl) phenyl] -3 - methoxy methyl acrylate (by machine translation)
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The invention has the activity of inhibiting crop bacteria [(6 - substituted - pyrimidine - 4 - oxyacetyl) phenyl] - 3 - methoxy methyl acrylate, relates to the technical field of biochemistry. It has the following general structure: It is inhibiting the cucumber wilt disease, peanut pinguis bacteria, germ, galenical wheat, maize leaf spot, watermelon anthrax bacteria, donor bacteria and other applications has good activity. (by machine translation)
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- Design, synthesis, and antifungal activities of new β-methoxyacrylate analogues
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Strobilurins have become one of the most important classes of agricultural fungicides. To search for new strobilurin derivatives with high activity against resistant pathogens, a series of new β-methoxyacrylate analogues containing substituted pyrimidine in the side chain with strobilurin pharmacophore were synthesized and their biological activities were tested. The compounds were confirmed and characterized by 1H-NMR, elemental analysis and mass spectroscopy. The bioassays indicated that most of the compounds 1 exhibited potent antifungal activities against Colletotrichum orbiculare, Botrytis cinerea Pers and Phytophthora capsici Leonian at a concentration of 50 μg mL-1. Notably, compound 1b (R = 2,5-dimethylphenyl) showed better antifungal activity against all the tested fungi than the commercial strobilurin fungicide azoxystrobin.
- Liu, Hui-Jun,Zhang, Xiang,Gao, Yong-Xin,Li, Jian-Zhong,Wang, Hui-Li
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