- A process for the preparation of nitrobenzene derivative
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The invention provides a preparation method of nitrobenzene derivatives, which comprises the following steps: mixing aromatic amino-compound with sodium perborate, a titanic acid catalyst and glacial acetic acid, and reacting to obtain nitrobenzene derivatives, wherein the titanic acid catalyst is prepared by reacting isopropyl titanate and oxydol, and the aromatic amino-compound is a compound with an electrophilic substitution group in the ortho-position of the amino group. By using the sodium perborate as the oxidizer and the titanic acid catalyst as the cocatalyst, the reaction yield is up to 80-85%, and the product purity is up to 99% above.
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Paragraph 0040; 0041; 0042
(2016/10/10)
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- Synthesis of novel quinazolinone derivatives with methyl (E)-2-(3-methoxy)acrylate moiety
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A new series of quinazolinone derivatives with methyl (E)-2-(3-methoxy) acrylate moiety have been designed and synthesized. All target compounds had been identified by 1H NMR spectrum, IR spectrum and HR-MS (high resolution mass spectrum). Three target compounds (10a, 10e, 10h) were chosen to preliminarily test the antibacterial activities, the results showed that all three target compounds exhibited antibacterial activities against three bacterial strains (Proteobacteria, Salmonella, Colibacillus).
- Dong, Kui-Kui,Zhou, Hua-Hong,Guo, A-Rong,Chen, Tian,Wang, Yu-Liang
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p. 1039 - 1042
(2013/05/08)
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