478272-66-1Relevant articles and documents
Fragmentation of nitrone triflates to 9-membered rings
Murphy, John A.,Mahesh, Mohan,McPheators, Gary,Vijaya Anand,McGuire, Thomas M.,Carlinga, Robert,Kennedy, Alan R.
, p. 3233 - 3236 (2008/02/11)
A new fragmentative rearrangement of nitrone derivatives to form 9-membered rings is reported. The fragmentations are triggered when nitrones are treated with triflic anhydride; a C-C bond antiperiplanar to the cleaving N-O bond is activated either by an oxygen lone pair or by an electron-rich aromatic ring. In the former case, further cyclization of the 9-membered intermediate leads to a rearranged condensed ring system, but when triggered by arenes, 9-membered ring amides are isolated.
Novel Catalytic Kinetic Resolution of Racemic Epoxides to Allylic Alcohols
Gayet, Arnaud,Bertilsson, Sophie,Andersson, Pher G.
, p. 3777 - 3779 (2007/10/03)
(Matrix Presented) The kinetic resolution of racemic epoxides via catalytic enantioselective rearrangement to allylic alcohols was investigated. Using the Li-salt of (1S,3R,4R)-3-(pyrrolidinyl)methyl-2-azabicyclo [2.2.1] heptane 1 as catalyst allowed both