479077-76-4

Basic information

• Product Name: CIL-102
• Synonyms: Ethanone, 1-[4-(furo[2,3-b]quinolin-4-ylamino)phenyl]-
• CAS NO: 479077-76-4
• Molecular Formula: C₁₉H₁₄N₂O₂
• Molecular Weight: 302.332
• Mol File: 479077-76-4.mol

Chemical Properties

• Boiling Point: 491°C at 760 mmHg
• Flash Point: 250.7°C
• Appearance: /solid
• Density: 1.265g/cm³
• Vapor Pressure: 8.73E-10mmHg at 25°C
• Refractive Index: 1.716
• Storage Temp.: −20°C
• Solubility: DMSO: 12 mg/mL
• CAS DataBase Reference: CIL-102(CAS DataBase Reference)
• NIST Chemistry Reference: CIL-102(479077-76-4)
• EPA Substance Registry System: CIL-102(479077-76-4)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 479077-76-4(Hazardous Substances Data)

Usage

Uses

CIL-102 is an inhibitor of Tubulin polymerization.

InChI:InChI=1/C20H15NO2/c1-13(22)14-6-8-16(9-7-14)21-20-17-5-3-2-4-15(17)12-19-18(20)10-11-23-19/h2-12,21H,1H3

Upstream product

• 111163-82-7 4-chlorofuro[2,3-b]quinoline 
• 99-92-3 p-aminobenzophenone 
• 629164-70-1 1-[4-(3-chlorofuro[2,3-b]quinolin-4-ylamino)phenyl]ethanone 
• 530-52-9 furo[2,3-b]quinolin-4(9H)-one 

Downstream Products

• 1310569-76-6 (E)-1-(4-(furo[2,3-b]quinolin-4-ylamino)phenyl)ethanone O-3-aminopropyl oxime 
• 1310569-81-3 (E)-1-(4-(furo[2,3-b]quinolin-4-ylamino)phenyl)ethanone O-4-morpholinobutyl oxime 
• 1310569-80-2 (E)-1-(4-(furo[2,3-b]quinolin-4-ylamino)phenyl)ethanone O-2-morpholinoethyl oxime 
• 1310569-75-5 (E)-1-(4-(furo[2,3-b]quinolin-4-ylamino)phenyl)ethanone O-2-(dimethylamino)ethyl oxime 
• 1310569-77-7 (E)-1-(4-(furo[2,3-b]quinolin-4-ylamino)phenyl)ethanone O-3-(dimethylamino)propyl oxime 
• 1310569-74-4 (E)-1-(4-(furo[2,3-b]quinolin-4-ylamino)phenyl)ethanone O-2-aminoethyl oxime 
• 1310569-78-8 (E)-1-(4-(furo[2,3-b]quinolin-4-ylamino)phenyl)ethanone O-2-(pyrrolidin-1-yl)ethyl oxime 
• 1310569-79-9 (E)-1-(4-(furo[2,3-b]quinolin-4-ylamino)phenyl)ethanone O-2-(piperidin-1-yl)ethyl oxime 

Relevant articles and documents

4-ANILINO[2,3-b]QUINOLINE DERIVATIVES,THEIR PREPARATION PROCECC ANDPHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME

Disclosed herein are novel 4-anilino[2,3-b]quinoline derivatives of formula (I): wherein each of the substituents is given the definition as set forth in the Specification and claims. Also disclosed are the preparation process of these derivatives, and th

Synthesis and cytotoxic evaluation of some 4-anilinofuro[2,3-b]quinoline derivatives

Some 4-anilinofuro[2,3-b] quinoline derivatives were synthesized from dictamnine, a natural alkaloid, and evaluated for their cytotoxicity in the NCI's full panel of 60 human cancer cell lines derived from nine cancer cell types, including leukemia, non-s