486414-83-9

Basic information

• Product Name: (1-Methyl-1H-imidazol-4-yl)methylamine
• Synonyms: C-(1-METHYL-1H-IMIDAZOL-4-YL)-METHYLAMINE;(1-METHYL-1H-IMIDAZOL-4-YL)METHYLAMINE;4-(AMINOMETHYL)-1-METHYL-1H-IMIDAZOLE;4-(Aminomethyl)-1-methyl-1H-imidazole 97%;(1-Methyl-1H-imidazol-4-yl)methylamine ,97%;(1-methyl-1H-imidazol-4-yl)methanamine;(1-Methyl-1H-iMidazol-4-yl)MethylaMine hydrochloride;4-(AMinoMethyl)-1-Methyli...
• CAS NO: 486414-83-9
• Molecular Formula: C5H9N3
• Molecular Weight: 111.15
• Mol File: 486414-83-9.mol

Chemical Properties

• Boiling Point: 104 °C
• Flash Point: 130.51 °C
• Appearance: /
• Density: 1.16 g/cm³
• Storage Temp.: 2-8°C
• PKA: 8.23±0.29(Predicted)
• CAS DataBase Reference: (1-Methyl-1H-imidazol-4-yl)methylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (1-Methyl-1H-imidazol-4-yl)methylamine(486414-83-9)
• EPA Substance Registry System: (1-Methyl-1H-imidazol-4-yl)methylamine(486414-83-9)

Safety Data

• Hazard Codes: C,Xn
• Statements: 34-22-41-37/38
• Safety Statements: 26-36/37/39-45-23-39
• RIDADR: 2735
• Hazardous Substances Data: 486414-83-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(1-Methyl-1H-imidazol-4-yl)methylamine is used as a building block for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Metal-Mediated Catalysis:
(1-Methyl-1H-imidazol-4-yl)methylamine is used as a potential ligand in metal-mediated catalysis, facilitating chemical reactions and improving the efficiency of certain synthesis processes.
Used in Synthesis of Bioactive Molecules:
(1-Methyl-1H-imidazol-4-yl)methylamine is used as a precursor for the synthesis of various bioactive molecules, which have potential applications in medicine, agriculture, and other fields.
Used in Production of Agrochemicals:
(1-Methyl-1H-imidazol-4-yl)methylamine is used as an intermediate in the production of agrochemicals, such as pesticides and herbicides, to enhance crop protection and yield.

Upstream product

• 143165-09-7 1-methyl-1H-imidazole-4-carbonyl chloride 
• 41716-18-1 1-methylimidazole-4-carboxylic acid 
• 129993-47-1 1-methyl-1H-imidazole-4-carboxylic acid amide 

Downstream Products

• 1072804-41-1 2-(1-(4-fluorobenzyl)-5-oxo-1H-1,2,4-triazol-4(5H)-yl)-4-methyl-N-((1-methyl-1H-imidazol-4-yl)methyl)thiazole-5-carboxamide 

Relevant articles and documents

HETEROARYL ALKYLENE SUBSTITUTED 2-OXOQUINAZOLINE DERIVATIVES AS INHIBITORS OF METHIONINE ADENOSYLTRANSFERASE 2A

Disclosed herein are certain heteroaryl alkylene substituted 2-oxoquinazoline derivatives of Formula (I): (I) that are methionine adenosyltransferase 2A (MAT2A) inhibitors. Also disclosed are pharmaceutical compositions comprising such compounds and methods of treating diseases treatable by inhibition of MAT2A such as cancer, including cancers characterized by reduced or absence of methylthioadenosine phosphorylase (MTAP) activity.

SMALL MOLECULE ACTIVATORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) AND USES THEREOF

Provided herein are small molecule activators of Nicotinamide Phosphoribosyltransferase (NAMPT), compositions comprising the compounds, and methods of using the compounds and compositions.

Thiazole benzamide derivatives and pharmaceutical compositions for inhibiting cell proliferation, and methods for their use

Aminothiazole compounds with mono-/di-substituted benzamide are represented by the Formula (I), and their pharmaceutically acceptable salts, pharmaceutically acceptable prodrugs, pharmaceutically active metabolites, and pharmaceutically acceptable salts of said metabolites are described. These agents modulate and/or inhibit the cell proliferation and activity of protein kinases and are useful as pharmaceuticals for treating malignancies and other disorders.