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[4-(2-Hydroxy-ethyl)-pyridin-3-yl]-carbamic acid tert-butyl ester is a carbamate ester chemical compound with the molecular formula C13H19N3O3. It features a pyridine ring with a hydroxyethyl substituent at the 4-position and a carbamic acid tert-butyl ester at the 3-position. The tert-butyl ester group serves as a protecting group in organic synthesis, allowing for mild deprotection to reveal the free carbamic acid. [4-(2-Hydroxy-ethyl)-pyridin-3-yl]-carbamic acid tert-butyl ester's chemical properties and reactivity make it a valuable pharmaceutical intermediate for synthesizing various pharmaceuticals and biologically active compounds.

486422-87-1

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486422-87-1 Usage

Uses

Used in Pharmaceutical Synthesis:
[4-(2-Hydroxy-ethyl)-pyridin-3-yl]-carbamic acid tert-butyl ester is used as a pharmaceutical intermediate for the synthesis of various pharmaceuticals and biologically active compounds. Its unique structure and reactivity contribute to the development of new drugs with potential therapeutic applications.
Used in Organic Synthesis:
In the field of organic synthesis, [4-(2-Hydroxy-ethyl)-pyridin-3-yl]-carbamic acid tert-butyl ester is used as a protecting group for carbamic acid. The tert-butyl ester group can be easily removed under mild conditions, making it a versatile tool for protecting sensitive functional groups during complex organic reactions.
Used in Drug Development:
[4-(2-Hydroxy-ethyl)-pyridin-3-yl]-carbamic acid tert-butyl ester is utilized in drug development for creating novel pharmaceuticals with improved efficacy and selectivity. Its structural features allow for the design of targeted therapies, potentially leading to more effective treatments for various diseases and conditions.
Used in Research and Development:
In the research and development sector, [4-(2-Hydroxy-ethyl)-pyridin-3-yl]-carbamic acid tert-butyl ester serves as a key compound for studying the structure-activity relationships of various biologically active molecules. This understanding can guide the design of more potent and selective drug candidates.
Used in Chemical Libraries:
[4-(2-Hydroxy-ethyl)-pyridin-3-yl]-carbamic acid tert-butyl ester is also used in the creation of chemical libraries for high-throughput screening. These libraries contain a diverse array of compounds that can be tested for their biological activities, potentially leading to the discovery of new therapeutic agents.

Check Digit Verification of cas no

The CAS Registry Mumber 486422-87-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,8,6,4,2 and 2 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 486422-87:
(8*4)+(7*8)+(6*6)+(5*4)+(4*2)+(3*2)+(2*8)+(1*7)=181
181 % 10 = 1
So 486422-87-1 is a valid CAS Registry Number.

486422-87-1Downstream Products

486422-87-1Relevant articles and documents

Preparation of azaindolines and benzoyl substituted azaindolines: Precursors of triazabenzo[cd]azulen-9-one PDE4 inhibitors

Badland, Matthew,Devillers, Ingrid,Durand, Corinne,Fasquelle, Véronique,Gaudillire, Bernard,Jacobelli, Henry,Manage, Ajith C.,Pevet, Isabelle,Puaud, Jocelyne,Shorter, Anthony J.,Wrigglesworth, Roger

, p. 5292 - 5296 (2011/10/30)

The syntheses of various substituted azaindolines are described. Azaindolines were identified as potential key intermediates towards new PDE4 inhibitors.

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