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491852-44-9

2-Bromo-1,5-difluoro-3-methoxybenzene is an organic compound characterized by its unique molecular structure, which consists of a benzene ring with a bromine atom at the 2-position, two fluorine atoms at the 1 and 5 positions, and a methoxy group at the 3-position. This chemical is known for its potential applications in the synthesis of pharmaceuticals and agrochemicals, as well as in the production of various specialty chemicals. Due to its specific functional groups, it can participate in a range of chemical reactions, such as nucleophilic substitutions, electrophilic aromatic substitutions, and elimination reactions, making it a versatile building block in organic chemistry. The compound's properties, such as its reactivity and stability, are influenced by the presence of electron-withdrawing fluorine atoms and the electron-donating methoxy group, which can affect its behavior in various chemical transformations.

491852-44-9

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491852-44-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 491852-44-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,9,1,8,5 and 2 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 491852-44:
(8*4)+(7*9)+(6*1)+(5*8)+(4*5)+(3*2)+(2*4)+(1*4)=179
179 % 10 = 9
So 491852-44-9 is a valid CAS Registry Number.

491852-44-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-bromo-1,5-difluoro-3-methoxybenzene

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:491852-44-9 SDS

491852-44-9Relevant articles and documents

RADIOLABELLED mGluR2 PET LIGANDS

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Paragraph 0176; 0188, (2013/09/12)

The present invention relates to novel, selective, radiolabelled mGluR2 ligands which are useful for imaging and quantifying the metabotropic glutamate receptor mGluR2 in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue, cells or a host, in vitro or in vivo and to precursors of said compounds.

Synthesis, evaluation, and radiolabeling of new potent positive allosteric modulators of the metabotropic glutamate receptor 2 as potential tracers for positron emission tomography imaging

Andres, Jose-Ignacio,Alcazar, Jesus,Cid, Jose Maria,De Angelis, Meri,Iturrino, Laura,Trabanco, Andres A.,Langlois, Xavier,Lavreysen, Hilde,Celen, Sofie,Bormans, Guy

, p. 8685 - 8699,15 (2020/09/16)

The synthesis and in vitro and in vivo evaluation of a new series of 7-(phenylpiperidinyl)-1,2,4-triazolo[4,3-a]pyridines, which were conveniently radiolabeled with carbon-11, as potential positron emission tomography (PET) radiotracers for in vivo imagin

RADIOLABELLED mGLuR2 PET LIGANDS

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Page/Page column 31, (2012/05/31)

The present invention relates to novel, selective, radiolabelled mGluR2 ligands which are useful for imaging and quantifying the metabotropic glutamate receptor mGluR2 in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue, cells or a host, in vitro or in vivo and to precursors of said compounds.

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