- The Reaction of Alkyl-substituted Thioanisoles with PCl3 and AlCl3: a Route to Benzothiadiphospholobenzothiadiphosphole Derivatives
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The synthesis of benzothiadiphospholobenzothiadiphosphole derivatives starting from alkyl-substituted thioanisoles and PCl3-AlCl3 is reported.The reaction is carried out at reflux in the absence of solvent and the yields are dependent on the starting sulphide.These new heterocycles can be purified by simple filtration on a Florisil column and have been characterized by 1H-, 13C-, (1H)31P-n.m.r. and mass spectroscopy analyses.New unexpected findings are also described.
- Baccolini, Graziano,Mezzina, Elisabetta,Todesko, Paolo Edgardo
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p. 3281 - 3284
(2007/10/02)
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- MOESSBAUER AND NUCLEAR MAGNETIC RESONANCE SPECTROSCOPIC STUDIES ON 'MYOCRISIN', 'SOLGANOL', 'AURANOFIN', AND RELATED GOLD(I) THIOLATES
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A large number of gold(I) thiolates, , have been prepared in which the R group is an alkyl, aryl, carboxylic acid, amino acid, or heterocycle.Most are highly insoluble in all common solvents, but (R' = Et, iPr, sBu, or tBu) dissolv
- Al-Sa'ady, Ali K. H.,Moss, Karen,McAuliffe, Charles A.,Parish, R. V. ("Dick")
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p. 1609 - 1616
(2007/10/02)
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- Reaction of Phosphinyl and Phosphinothioyl Disulfides with Diazomethane
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Four kinds of 4-substituted phenyl diethoxyphosphinyl disulfide (substituents: H, CH3, C2H5, Cl) and phenyl diethoxyphosphinothioyl disulfide reacted readily with diazomethane.The phosphinyl disulfides produced diethyl (4-substituted phenylthio)methyl phosphorothionate and the isomer, diethyl S-(4-substituted phenylthio)methyl phosphorothiolate, as the main products, whereas the phosphinothioyl disulfide produced only diethyl S-(phenylthio)methyl phosphorodithioate.The possible mechanism involved is as follows: the S-S bond in (EtO)2P(X)-S-S-C6H4R (X=O or S) is cleaved by nucleophilic attack of diazomethane at the sulfur atom bonded to the phenyl group to produce and (+)N2CH2-S-C6H4R; the latter reacts with the former with loss of nitrogen; therefore, when X is O, two compounds, (EtO)2P(S)-O-CH2-S-C6H4R and (EtO)2P(O)-S-CH2-S-C6H4R, are produced, when X is S, only (EtO)2P(S)-S-CH2-S-C6H4R is obtained.
- Miyamoto, Toru,Yamamoto, Izuru
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p. 2581 - 2586
(2007/10/02)
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- Antiallergic cyclic sulphur compounds
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Certain tricyclic thioxanthone-10,10-dioxide compounds each of which is substituted in the 1-,2-,3- or 4-position by a carboxyl or (5-tetrazolyl) group and each of which is optionally substituted in the 5-,6-,7- or 8-position by a second carboxyl or (5-tetrazolyl) group or a substituent selected from cyano, halogen, nitro, alkyl, alkoxy, acyl, amino, acylamino, thioalkyl, alkylsulphinyl and alkylsulphonyl, as well as salts, and optionally substituted esters and amides of the carboxyl substituted compounds and alkyl derivatives of the tetrazolyl substituted compounds, are useful for the relief or prophylaxis of allergic conditions.
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- Cyclic sulphur compounds
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Certain tricyclic thioxanthone-10,10-dioxide compounds each of which is substituted in the 1-,2-,3- or 4-position by a carboxyl or (5-tetrazolyl) group and each of which is optionally substituted in the 5-,6-,7- or 8-position by a second carboxyl or (5-tetrazolyl) group or a substituent selected from cyano, halogen, nitro, alkyl, alkoxy, acyl, amino, acylamino, thioalkyl, alkylsulphinyl and alkylsulphonyl, as well as salts, and optionally substituted esters and amides of the carboxyl substituted compounds and alkyl derivatives of the tetrazolyl substituted compounds, are useful for the relief or prophylaxis of allergic conditions.
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