- Intramolecular nucleophilic substitution of ω-haloalkylphosphine derivatives
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ω-Haloalkylphosphine derivatives undergo the intramolecular nucleophilic substitution reaction upon treatment with a strong base, yielding either cycloalkylphosphine derivatives or heterocyclic phosphine derivatives. The selectivity of the cyclization of
- Pawe?, Wo?nicki,Korzeniowska, Ewelina,Stankevic, Marek
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p. 10271 - 10296
(2018/02/27)
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- Novel phosphine ligands
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The invention is concerned with new phosphine ligands of the formula I wherein R1 and R2 are independently of each other alkyl, aryl, cycloalkyl or heteroaryl, said alkyl, aryl, cycloalkyl or heteroaryl may be substituted by alkyl, alkoxy, halogen, hydroxy, amino, mono- or dialkylamino, aryl, —SO2—R7, —SO3?, —CO—NR8R8′, carboxy, alkoxycarbonyl, trialkylsilyl, diarylalkylsilyl, dialkylarylsilyl or triarylsilyl; R3 is alkyl, cycloalkyl, aryl or heteroaryl; R4′ and R4 signify independently of each other hydrogen, alkyl or optionally substituted aryl; or R4′ and R4 together with the C-atom they are attached to form a 3-8-membered carbocyclic ring; dotted line is absent or is present and forms a double bond; R5 and R6 are independently of each other hydrogen, alkyl or aryl; or linked together to form a 3-8-membered carbocyclic ring or an aromatic ring; R7 is alkyl, aryl or NR8R8′; and R8 and R8′ are independently of each other hydrogen, alkyl or aryl; metal complexes with such ligands as well as the use of such metal complexes as catalysts in asymmetric reactions.
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Page/Page column 19
(2010/11/27)
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- A one-pot synthesis of 1-substituted cyclic phosphine sulfides by simultaneous addition of bis- and mono-grignard reagents to a new efficient phosphorus donating reagent
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The synthesis of the reported cyclic phosphine sulfides (4, 5, 6) is carried out in good yields in a one-pot reaction with simultaneous addition of the three reagents (1, BrMgCH2(CH2)(n)CH2MgBr, RMgBr) and final treatment with sulfur. The new phosphorus donating reagent benzothiadiphosphole 1 is an inexpensive, facile to prepare, and air-insensitive solid.
- Baccolini,Boga,Negri
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p. 1685 - 1687
(2007/10/03)
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