4963-90-0

Upstream product

• 4963-85-3 but-3-enyl-phenyl-phosphane 
• 1707-00-2 dimethylphenylphosphine sulfide 
• 644-97-3 Dichlorophenylphosphine 
• 13595-56-7 dilithium phenylphosphide 
• 23708-47-6 1,4-bis(bromomagnesium)butane 
• 3302-87-2 1-phenylphospholane 

Downstream Products

• 935732-37-9 2-[(2-hydroxy-2-phenyl)ethyl]-1-phenylphospholane-1-sulfide 
• 4963-91-1 1-phenylphospholane-1-oxide 
• 3302-87-2 1-phenylphospholane 

Relevant academic research and scientific papers

Intramolecular nucleophilic substitution of ω-haloalkylphosphine derivatives

ω-Haloalkylphosphine derivatives undergo the intramolecular nucleophilic substitution reaction upon treatment with a strong base, yielding either cycloalkylphosphine derivatives or heterocyclic phosphine derivatives. The selectivity of the cyclization of

Novel phosphine ligands

The invention is concerned with new phosphine ligands of the formula I wherein R1 and R2 are independently of each other alkyl, aryl, cycloalkyl or heteroaryl, said alkyl, aryl, cycloalkyl or heteroaryl may be substituted by alkyl, alkoxy, halogen, hydroxy, amino, mono- or dialkylamino, aryl, —SO2—R7, —SO3?, —CO—NR8R8′, carboxy, alkoxycarbonyl, trialkylsilyl, diarylalkylsilyl, dialkylarylsilyl or triarylsilyl; R3 is alkyl, cycloalkyl, aryl or heteroaryl; R4′ and R4 signify independently of each other hydrogen, alkyl or optionally substituted aryl; or R4′ and R4 together with the C-atom they are attached to form a 3-8-membered carbocyclic ring; dotted line is absent or is present and forms a double bond; R5 and R6 are independently of each other hydrogen, alkyl or aryl; or linked together to form a 3-8-membered carbocyclic ring or an aromatic ring; R7 is alkyl, aryl or NR8R8′; and R8 and R8′ are independently of each other hydrogen, alkyl or aryl; metal complexes with such ligands as well as the use of such metal complexes as catalysts in asymmetric reactions.

A one-pot synthesis of 1-substituted cyclic phosphine sulfides by simultaneous addition of bis- and mono-grignard reagents to a new efficient phosphorus donating reagent

The synthesis of the reported cyclic phosphine sulfides (4, 5, 6) is carried out in good yields in a one-pot reaction with simultaneous addition of the three reagents (1, BrMgCH2(CH2)(n)CH2MgBr, RMgBr) and final treatment with sulfur. The new phosphorus donating reagent benzothiadiphosphole 1 is an inexpensive, facile to prepare, and air-insensitive solid.