496810-71-0

Basic information

• Product Name: N-(4-ethylphenyl)-N'-(4-fluorobenzoyl)thiourea
• Synonyms: N-(4-ethylphenyl)-N'-(4-fluorobenzoyl)thiourea
• CAS NO: 496810-71-0
• Molecular Formula: C16H15FN2OS
• Molecular Weight: 302.3665032
• Mol File: 496810-71-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(4-ethylphenyl)-N'-(4-fluorobenzoyl)thiourea(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-ethylphenyl)-N'-(4-fluorobenzoyl)thiourea(496810-71-0)
• EPA Substance Registry System: N-(4-ethylphenyl)-N'-(4-fluorobenzoyl)thiourea(496810-71-0)

Safety Data

• Hazardous Substances Data: 496810-71-0(Hazardous Substances Data)

Upstream product

• 1147550-11-5 ammonium thiocyanate 
• 403-43-0 4-fluorobenzoyl chloride 
• 589-16-2 4-aminoethylbenzene 

Relevant articles and documents

Synthesis of novel thiazolidine-4-one derivatives and their anticancer activity

This paper describes the synthesis of a novel series of 1,3-thiazolidine-4-ones 6a-n by cycloaddition reaction of N-aryl-N'-acyl thioureas 4a-k with acetylenic esters 5a-b under microwave irradiation and solvent free conditions. Our method, compared to conventional heating conditions has the benefit of higher reaction yield and shorter reaction times. Structural confirmation and characterization of products based on the analytical, chemical, and spectral analysis was confirmed. Cellular investigations showed that the target synthesized thiazolidine-4-ones are toxic and could be used as anticancer agents for MKN-45 gastric adenocarcinoma cells.