403-43-0

Basic information

• Product Name: 4-Fluorobenzoyl chloride
• Synonyms: 4-fluoro-benzoylchlorid;Benzoyl chloride, p-fluoro-;para-Fluorobenzoyl chloride;p-Fluorobenzoic acid chloride;P-FLUOROBENZOYL CHLORIDE;FLUOROBENZOYL(4-) CHLORIDE;LABOTEST-BB LTBB000747;4-Fluorobenozylchloride
• CAS NO: 403-43-0
• Molecular Formula: C₇H₄ClFO
• Molecular Weight: 158.56
• EINECS: 206-961-4
• Product Categories: Benzene derivatives;Fluorobenzene;Acid Halides;Carbonyl Compounds;Organic Building Blocks;Carbonyl Compounds
• Mol File: 403-43-0.mol
• Article Data: 144

Chemical Properties

• Melting Point: 10-12 °C(lit.)
• Boiling Point: 82 °C20 mm Hg(lit.)
• Flash Point: 180 °F
• Appearance: Clear colorless to light yellow/Liquid
• Density: 1.342 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.000277mmHg at 25°C
• Refractive Index: n20/D 1.532(lit.)
• Storage Temp.: 2-8°C
• Water Solubility: Reacts with water.
• Sensitive: Lachrymatory
• BRN: 386215
• CAS DataBase Reference: 4-Fluorobenzoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Fluorobenzoyl chloride(403-43-0)
• EPA Substance Registry System: 4-Fluorobenzoyl chloride(403-43-0)

Safety Data

• Hazard Codes: C
• Statements: 34-36/37-14
• Safety Statements: 26-36/37/39-45-28A-27
• RIDADR: UN 3265 8/PG 2
• WGK Germany: 3
• F: 10-19
• TSCA: T
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 403-43-0(Hazardous Substances Data)

Usage

Chemical Properties

clear colourless to light yellow liquid

Uses

It is used in the synthesis of polyphenylene ether and thioether ketones and also in the synthesis fluorinated poly(aryl ether ketone)s containing 1,4-naphthalene moieties. It is also used as a raw material in engineering of plastics.

General Description

4-Fluorobenzoyl chloride undergoes Friedel-Crafts acylation reaction with 2,6-dimethylnaphthalene to give 1,5-bis(4-fluorobenzoyl)-2,6-dimethylnaphthalene.

InChI:InChI=1/C6H4FNO2/c7-5-2-1-4(3-8-5)6(9)10/h1-3H,(H,9,10)

Upstream product

• 459-57-4 4-fluorobenzaldehyde 
• 352-32-9 p-fluorotoluene 
• 93342-79-1 1-(4-Fluoro-benzoyl)-3-methyl-3H-imidazol-1-ium; chloride 
• 456-22-4 4-Fluorobenzoic acid 
• 21615-34-9 2-Methoxybenzoyl chloride 
• 403-33-8 methyl 4-flurobenzoate 
• 24167-56-4 N,N-dimethyl-4-fluorobenzamide 
• 402-42-6 4-fluoro-1-trichloromethylbenzene 
• 13656-36-5 3,5-dichloro-2,4,6-trifluorobenzoic acid 
• 316142-60-6 N-(4-cyanophenyl)-4-fluorobenzamide 
• 707-74-4 (trichloromethyl)mesitylene 
• 352-34-1 4-fluoro-1-iodobenzene 
• 141-75-3 butyryl chloride 
• 14432-12-3 4-Amino-2-chloropyridine 

Downstream Products

• 2561-29-7 6-(4-fluoro-benzoylamino)-benzo[1,3]dioxole-5-carboxylic acid methyl ester 
• 579-49-7 2-(4-fluorobenzoyl)thiophene 
• 4146-56-9 4-fluoro-benzoic acid-(2-piperidino-ethyl ester) 
• 325-97-3 4-fluoro-N-(pyridine-2-yl)benzamide 
• 325-98-4 4-fluoro-N-(pyrimidin-2-yl)benzamide 
• 1893-23-8 4-fluoro-benzoic acid-(1-phenyl-2-pyrrolidino-ethyl ester); hydrochloride 
• 442-72-8 4-fluoro-N-(naphthalen-1-yl)benzamide 
• 345-92-6 4,4'-Difluorobenzophenone 
• 2069-41-2 (4-bromophenyl)-(4-fluorophenyl)methanone 
• 451-28-5 rac-2-(4-fluorobenzamido)propanoic acid 
• 532-90-1 4-fluoro-benzoic acid-(3-diethylamino-propyl ester) 
• 399-12-2 4-fluoro-benzoic acid-(2-dipropylamino-ethyl ester) 
• 399-14-4 4-fluoro-benzoic acid-(3-dipropylamino-propyl ester) 
• 451-60-5 4-fluoro-benzoic acid-(2-dibutylamino-ethyl ester) 

Relevant articles and documents

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