New spirohydantoin derivatives - Synthesis, pharmacological evaluation, and molecular modeling study
A series of new arylpiperazinylpropyl derivatives of 8/6-phenyl-1,3-diazaspiro[4.5]decan-2,4-dione and spiro[imidazolidine-4,1′-indene/naphthalene]-2,5-dione was synthesized and their affinity was evaluated toward serotonin 5-HT1A, 5-HT2A
Novel spirohydantoin derivative as a potent multireceptor-active antipsychotic and antidepressant agent
Abstract A series of novel spirohydantoin derivatives with arylpiperazinylbutyl moiety were synthesized and evaluated for serotonin 5-HT1A, 5-HT2A, 5-HT7 and dopamine D2 receptors. Based on these data, four comp
Czopek, Anna,Ko?aczkowski, Marcin,Bucki, Adam,Byrtus, Hanna,Paw?owski, Maciej,Kazek, Grzegorz,Bojarski, Andrzej J.,Piaskowska, Agata,Kalinowska-T?ücik, Justyna,Partyka, Anna,Weso?owska, Anna
p. 3436 - 3447
(2015/08/03)
Stereochemistry of the conventional and modified Bucherer-Bergs reactions of 2-substituted cyclohexanones
The configurations of the spiro-hydantoins produced from 2-methyl- and 2-phenylcyclohexanone, 2,6-dimethylcyclohexanone, and dl-menthone by either the conventional Bucherer-Bergs (B.-B.) reaction, or a variant employing COS or CS2 in place of C
Sacripante, Guerino,Edward, John T.
p. 1982 - 1987
(2007/10/02)
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