501347-05-3Relevant articles and documents
An intramolecular Michael reaction strategy for the synthesis of 2,6-disubstituted-3-piperidinols
Sengupta, Saumitra,Mondal, Somnath
, p. 7983 - 7986 (2002)
A new synthetic strategy for 2,6-disubstituted-3-hydroxypiperidines via intramolecular Michael reaction of an α-amino-β-hydroxy-δ-acrylate is described. The latter was derived from L-alanine in a few steps via the key intermediacy of an enantiopure γ-amino-β-keto sulfone.