Synthesis of (±)-(2-methylenecyclopropyl)glycine and (±)-4-[amino(carboxymethyl)]spiro[2.2]pentane-1-carboxylie acid
A facile method for the preparation of racemic cyclopropylglycines is described, involving oxidation of cyclopropylcarbinols followed by a Bucherer-Berg reaction with sequential hydrolysis of the hydantoins obtained. Georg Thieme Verlag Stuttgart.
Averina, Elena B.,Yashin, Nikolai V.,Grishin, Yurii K.,Kuznetsova, Tamara S.,Zefirov, Nikolai S.