503599-28-8 Usage
Uses
Used in Organic Synthesis:
α-D-Glucopyranuronic Acid Methyl Ester 2,3,4-Tribenzoate 1-Methanesulfonate is used as a reactant in the field of organic synthesis for the preparation of novel quaternary glucuronyl reagents. These reagents are essential for the synthesis of tertiary amines, which are crucial components in the development of various pharmaceuticals and chemical compounds.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, α-D-Glucopyranuronic Acid Methyl Ester 2,3,4-Tribenzoate 1-Methanesulfonate is utilized as a key intermediate in the synthesis of drugs that target specific biological pathways. Its unique structure allows for the creation of molecules with enhanced properties, such as improved solubility, stability, and bioavailability, which are vital for the effectiveness of pharmaceutical products.
Used in Chemical Research:
α-D-Glucopyranuronic Acid Methyl Ester 2,3,4-Tribenzoate 1-Methanesulfonate is also employed in chemical research as a model compound for studying the properties and reactivity of complex organic molecules. This helps researchers gain a deeper understanding of the underlying chemical mechanisms and develop new strategies for the synthesis of novel compounds with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 503599-28-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,0,3,5,9 and 9 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 503599-28:
(8*5)+(7*0)+(6*3)+(5*5)+(4*9)+(3*9)+(2*2)+(1*8)=158
158 % 10 = 8
So 503599-28-8 is a valid CAS Registry Number.
503599-28-8Relevant articles and documents
Applicability of methyl 2,3,4-tri-O-benzoyl-1-methanesulfonyl-α-d-glucopyranuronate as a novel quaternary glucuronyl reagent for tertiary amines
Araya, Ichiro,Akita, Hiroyuki
, p. 1213 - 1223 (2008/12/20)
Applicability of a methyl 2,3,4-tri-O-benzoyl-1-methanesulfonyl-α-D-glucopyranuronate 3 as a novel quaternary glucuronyl reagent was investigated. The reaction of 3 with an aromatic tertiary amines such as pyridine derivatives or imidazole derivatives proceeded to give quaternary N-glucuronides in a moderate yields, but the reaction of 3 with an aliphatic tertiary amine did not occur. In case of the reaction of 3 with nicotine which has aromatic and aliphatic tertiary amines in the molecule, the reaction proceeded selectively on the pyridine ring to give the corresponding N-glucuronide. The present reagent was considered to be useful for the formation of N-quaternary glucuronide from aromatic tertiary amines.
Synthesis of the metabolites of 4-(2-methyl-1H-imidazol-1-yl)-2,2- diphenylbutanamide (KRP-197/ONO-8025)
Araya, Ichiro,Tsubuki, Takeshi,Saito, Tatsuhiro,Numata, Makoto,Akita, Hiroyuki
, p. 1039 - 1043 (2008/02/10)
We synthesized the six presumed metabolites (2-7) of 4-(2-methyl-1H- imidazol-1-yl)-2,2-diphenylbutanamide [KRP-197/ONO-8025, 1], a urinary incontinence therapeutic agent, in order to confirm the structures of the metabolites. Metabolite (2) was synthesiz
