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Ethyl 2-(morpholin-2-yl)acetate is a versatile chemical compound synthesized through the condensation of ethyl acetoacetate and morpholine. It is characterized by its ability to act as a chelating agent and serves as a valuable building block in the synthesis of pharmaceutical drugs, agrochemicals, and specialty chemicals. Its utility as a solvent in certain chemical reactions further enhances its importance in the pharmaceutical and chemical industries.

503601-25-0

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503601-25-0 Usage

Uses

Used in Pharmaceutical Industry:
Ethyl 2-(morpholin-2-yl)acetate is used as a building block for the synthesis of various pharmaceutical drugs. Its chelating properties and potential as a drug intermediate make it a valuable component in the development of new medications.
Used in Agrochemical Production:
In the agrochemical industry, Ethyl 2-(morpholin-2-yl)acetate is utilized in the production of various agrochemicals, contributing to the development of effective and innovative products for agricultural applications.
Used in Specialty Chemicals Manufacturing:
Ethyl 2-(morpholin-2-yl)acetate is employed in the manufacturing of specialty chemicals, where its unique properties and reactivity are harnessed to create high-value products for specific applications.
Used as a Solvent in Chemical Reactions:
Ethyl 2-(morpholin-2-yl)acetate is used as a solvent in certain chemical reactions and processes, facilitating the desired transformations and contributing to the efficiency and effectiveness of these procedures.

Check Digit Verification of cas no

The CAS Registry Mumber 503601-25-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,0,3,6,0 and 1 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 503601-25:
(8*5)+(7*0)+(6*3)+(5*6)+(4*0)+(3*1)+(2*2)+(1*5)=100
100 % 10 = 0
So 503601-25-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H15NO3/c1-2-11-8(10)5-7-6-9-3-4-12-7/h7,9H,2-6H2,1H3

503601-25-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 2-morpholin-2-ylacetate

1.2 Other means of identification

Product number -
Other names ethyl 2-(morpholin-2-yl)acetate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:503601-25-0 SDS

503601-25-0Relevant articles and documents

Novel anticancer compound and usage thereof

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Paragraph 0032; 0033; 0040; 0041; 0042; 0043, (2019/06/27)

The invention provides a novel anticancer compound. The novel anticancer compound is a compound shown in chemical formula 1 in the description or pharmaceutically acceptable salt of the compound, andthe compound and the salt are active ingredients of a pharmaceutical composition for inhibiting the activity of hepatocyte growth factor receptor (c-Met) tyrosine kinase and pharmaceutical compositionfor preventing or curing excessive or abnormal proliferative diseases. The compound effectively inhibits the activity of the hepatocyte growth factor receptor tyrosine kinase, thereby being suitablefor treating the diseases with the characteristics of excessive or abnormal cell proliferation.

PYRIDYL DERIVATIVES AS BROMODOMAIN INHIBITORS

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Page/Page column 40, (2017/11/04)

The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.

BENZO[B]FURANS AS BROMODOMAIN INHIBITORS

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Page/Page column 71, (2017/11/06)

The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.

Discovery of novel selective norepinephrine inhibitors: 1-(2-morpholin-2-ylethyl)-3-aryl-1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxides (WYE-114152)

O'Neill, David J.,Adedoyin, Adedayo,Bray, Jenifer A.,Deecher, Darlene C.,Fensome, Andrew,Goldberg, Joel A.,Harrison, Jim,Leventhal, Liza,Mann, Charles,Mark, Lilly,Nogle, Lisa,Sullivan, Nicole R.,Spangler, Taylor B.,Terefenko, Eugene A.,Trybulski, Eugene J.,Uveges, Albert J.,Vu, An,Whiteside, Garth T.,Zhang, Puwen

supporting information; experimental part, p. 6824 - 6831 (2011/12/04)

Sequential modification of the previously identified 4-[3-aryl-2,2-dioxido- 2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ols led to the identification of a new series of 1-(2-morpholin-2-ylethyl)-3-aryl-1,3-dihydro- 2,1,3-benzothiadiazole 2,2-dioxides that are potent and selective inhibitors of the norepinephrine transporter over both the serotonin and dopamine transporters. One representative compound 10b (WYE-114152) had low nanomolar hNET potency (IC50 = 15 nM) and good selectivity for hNET over hSERT (>430-fold) and hDAT (>548-fold). 10b was additionally bioavailable following oral dosing and demonstrated efficacy in rat models of acute, inflammatory, and neuropathic pain.

Substituted morpholine-2S-acetic acid derivatives: SCH 50911 and related compounds as novel GABA(B) antagonists

Blythin, David J.,Kuo, Shen-Chun,Shue, Ho-Jane,McPhail, Andrew T.,Chapman, Richard W.,Kreutner, William,Rizzo, Charles,She, Hoyan S.,West, Robert

, p. 1529 - 1534 (2007/10/03)

The synthesis and GABA(B) antagonist activity of a series of substituted morpholine-2-acetic acid derivatives is described. Resolution of the lead compound from the series produces one active and one inactive enantiomer. X- ray analysis of a halogenated derivative (25) of the active enantiomer Sch 50911 (23) shows that it possesses the 2S configuration.

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