503860-58-0

Usage

Uses

Used in Mental Health Treatment:
(S)-2-(4-fluorophenyl)Morpholine hydrochloride is used as an antidepressant for treating depression, as it increases the levels of serotonin in the brain, leading to improved mood and reduced depressive symptoms.
Used in Anxiety Treatment:
(S)-2-(4-fluorophenyl)Morpholine hydrochloride is used as an anxiolytic agent for managing anxiety disorders, as it helps to regulate the levels of serotonin, which can contribute to a sense of calm and reduce anxiety.
Used in Obsessive-Compulsive Disorder (OCD) Treatment:
(S)-2-(4-fluorophenyl)Morpholine hydrochloride is used as a therapeutic agent for OCD, where it aids in controlling obsessions and compulsions by modulating serotonin levels in the brain.
Used in Pharmaceutical Industry:
(S)-2-(4-fluorophenyl)Morpholine hydrochloride is used as an active pharmaceutical ingredient (API) for the development of medications aimed at treating depression, anxiety, and OCD, due to its effectiveness in increasing serotonin levels in the brain.

Upstream product

• 18511-62-1 (2S)-2-(4-fluorophenyl)oxirane 
• 126534-42-7 (S)-1-chloro-2-hydroxy-2-(p-fluorophenyl)ethane 
• 456-04-2 2-Chloro-4'-fluoroacetophenone 
• 920796-74-3 (2S)-4-benzyl-2-(4-fluorophenyl)morpholine 
• 920796-73-2 (6S)-6-(4-fluorophenyl)-4-benzylmorpholine-3-one 
• 920797-21-3 N-benzyl-2-chloro-N-[(2S)-2-(4-fluorophenyl)-2-hydroxyethyl]acetamide 
• 18511-62-1 R-(-)-2-(4-fluorophenyl)oxirane 
• 403-29-2 2-bromo-4'-fluoroacetophenone 
• 1234372-12-3 (1S)-2-bromo-1-(4-fluorophenyl)ethan-1-ol 

Downstream Products

• 1449275-15-3 N-[(1R)-1-(4-{[(2S)-2-(4-fluorophenyl)morpholin-4-yl]methyl}phenyl)ethyl]methanesulfonamide hydrochloride 
• 503860-57-9 UDA-680 
• 1449275-13-1 N-[(1R)-1-(4-{[(2S)-2-(4-fluorophenyl)morpholin-4-yl]methyl}phenyl)ethyl]methanesulfonamide 
• 1266238-52-1 (S)-5'-fluoro-2-[2-(4-fluoro-phenyl)-morpholin-4-yl]-1-methyl-1H-[4,4']bipyrimidinyl-6-one 

Relevant academic research and scientific papers

2-(2-Phenylmorpholin-4-yl)pyrimidin-4(3H)-ones; A new class of potent, selective and orally active glycogen synthase kinase-3β inhibitors

A series of 2-(2-phenylmorpholin-4-yl)pyrimidin-4(3H)-ones was synthesized and examined for their inhibitory activity against glycogen synthase kinase-3β (GSK-3β). We found 21, 29 and 30 to possess potent in vitro GSK-3β inhibitory activity with good in vitro PK profiles. 21 demonstrated significant decrease of tau phosphorylation after oral administration in mice and excellent PK profiles.

NOVEL MORPHOLINYL DERIVATIVES USEFUL AS MOGAT-2 INHIBITORS

The present invention provides compounds of Formula I or a pharmaceutical salt thereof, methods of treating hypertriglyceridemia using the compounds; and a process for preparing the compounds.

INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF

The present invention relates to a production method of an optically active morpholine compound represented by the formula 10, which includes the following steps: wherein each symbol is as defined in the specification. The present invention also relates t