cas 50402-56-7, 1,5-EDANS | Articles data

Articles about 50402-56-7Total 6 be found

Redox-based selective fluorometric detection of homocysteine
Plasma homocysteine (Hcy) is an important risk factor for various diseases. A novel redox-sensitive fluorescent probe is developed for the selective detection of Hcy. A linear calibration curve has been obtained in buffer and plasma for the quantitative determination of Hcy in such media. This journal is
Peng, Hanjing,Wang, Ke,Dai, Chaofeng,Williamson, Samuel,Wang, Binghe
p. 13668 - 13671
(2014)
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Chemically modified dansyl probes: A fluorescent diagnostic for ion and proton detection in solution and in polymers
The fluorescence emission intensity of the dansyl group is significantly diminished upon appending an ethyldimethylamino group to the N1 nitrogen substituent. Addition of acids and metal ions (i.e., Zn2+) to solutions of trimethylethylenediamine naphthalene sulfonamide (trinsyl) 2 produces a >25-fold increase in fluorescence intensity. Trinsyl probe 2 has been used as a diagnostic for the diffusion of protons and metal ions in a network polymer as well as an optical reporter for the glass transition temperature.
O'Connor, Naphtali A.,Sakata, Steven T.,Zhu, Huide,Shea, Kenneth J.
p. 1581 - 1584
(2006)
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Fluorogenic Bifunctional trans-Cyclooctenes as Efficient Tools for Investigating Click-to-Release Kinetics
The inverse electron demand Diels–Alder pyridazine elimination reaction between tetrazines and allylic substituted trans-cyclooctenes (TCOs) is a key player in bioorthogonal bond cleavage reactions. Determining the rate of elimination of alkylamine substrates has so far proven difficult. Here, we report a fluorogenic tool consisting of a TCO-linked EDANS fluorophore and a DABCYL quencher for accurate determination of both the click and release rate constants for any tetrazine at physiologically relevant concentrations.
de Geus, Mark A. R.,Maurits, Elmer,Sarris, Alexi J. C.,Hansen, Thomas,Kloet, Max S.,Kamphorst, Kiki,ten Hoeve, Wolter,Robillard, Marc S.,Pannwitz, Andrea,Bonnet, Sylvestre A.,Codée, Jeroen D. C.,Filippov, Dmitri V.,Overkleeft, Herman S.,van Kasteren, Sander I.
supporting information
p. 9900 - 9904
(2020/06/05)

HSV-2 type-specific immunoassays using glycoprotein G2 peptides
The present invention relates to peptides that are derived from HSV-2 glycoprotein G2 and represent HSV-2 type-specific epitopes. The present invention also provides for compositions comprising these peptides for type-specific serological diagnosis of HSV-2 infection. Methods of using these peptides for type-specific detection of HSV-2 antibodies and differentiation of HSV-2 viral infection from HSV-1 and other herpes family viral infections are further provided.
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(2008/06/13)

Multiconstituent liquid lgG and IgM calibrators
A serum in which are dissolved at least two heterologous antibodies, which are independently IgG or IgM and which specifically bind to different antigens, serves as a calibrator for multi-analyte immunoassays.
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(2008/06/13)

Epididymis-specific defensin for evaluating and regulating male fertility
The present invention relates to the discovery that an epididymis-specific defensin, EP2D, plays an important role in regulating sperm motility and therefore male fertility. Provided are methods for evaluating male fertility based on the level of EP2D bound to sperm, kits for evaluating male fertility, and methods for enhancing or suppressing fertility in a male by regulating the level of EP2D and the binding between sperm and EP2D.
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(2008/06/13)