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Ethylenediamine (EDA) CAS:107-15-3 from fandachem
Cas No: 107-15-3
No Data No Data Metric Ton/Day Hangzhou Fandachem Co.,Ltd Contact Supplier
1,2-Ethanediamine CAS NO.107-15-3
Cas No: 107-15-3
USD $ 1.0-3.0 / Metric Ton 1 Metric Ton 10 Metric Ton/Day Hebei yanxi chemical co.,LTD. Contact Supplier
Ethylenediamine,CAS 107-15-3
Cas No: 107-15-3
USD $ 1.0-1.0 / Metric Ton 1 Metric Ton 3000 Metric Ton/Year Hefei TNJ chemical industry co.,ltd Contact Supplier
Amadis Chemical offer CAS#107-15-3;CAT#A801596
Cas No: 107-15-3
No Data 10 Milligram Amadis Chemical Co., Ltd. Contact Supplier
Ethylenediamine CAS: 107-15-3
Cas No: 107-15-3
USD $ 1.0-2.0 / Metric Ton 5 Metric Ton 2500 Metric Ton/Year Henan Sinotech Import&Export Corporation Contact Supplier
Factory Supply 1,2-Ethanediamine
Cas No: 107-15-3
No Data 100 Gram 1000 Metric Ton/Day Ality Chemical Corporation Contact Supplier
High Quality Pharmaceutical Intermediate CAS 107-15-3 1,2-Diaminoethane anhydrous
Cas No: 107-15-3
No Data 10 Gram 10 Metric Ton/Week Hubei XinRunde Chemical Co., Ltd Contact Supplier
TIANFU-CHEM - Ethylenediamine
Cas No: 107-15-3
No Data 1 Kilogram 10 Metric Ton/Month Henan Tianfu Chemical Co., Ltd. Contact Supplier
Ethylenediamine CAS NO.107-15-3 low price
Cas No: 107-15-3
No Data 1 Kilogram 100 Metric Ton/Week HUBEI AOKS BIO-TECH CO.,LTD Contact Supplier
Ethylenediamine WITH CAS:107-15-3
Cas No: 107-15-3
USD $ 81.0-90.0 / Kilogram 1 Kilogram 10000 Metric Ton/Month Baoji Guokang Healthchem co.,ltd Contact Supplier

107-15-3 Usage

Reactivity Profile

A base. Highly reactive with many compounds. Can react violently with acetic acid, acetic anhydride, acrolein, acrylic acid, acrylonitrile, allyl chloride, carbon disulfide, chlorosulfonic acid, epichlorohydrin, ethylene chlorohydrin, hydrogen chloride, mesityl oxide, nitric acid, oleum, AgClO4, sulfuric acid, beta-propiolactone and vinyl acetate. Incompatible with strong acids, strong oxidizers (perchlorate salts), and chlorinated organic compounds. Ethylenediamine is also incompatible with halogenated organic compounds and metal halides. May react with nitromethane and diisopropyl peroxydicarbonate. May ignite on contact with cellulose nitrate. Readily absorbs carbon dioxide from the air to give crusty solid deposits. . Ethylenediamine reacts violently with ethylene chlorohydrin. (Lewis, R.J., Sr. 1992. Sax's Dangerous Properties of Industrial Materials, 8th Edition. New York: Van Nostrand Reinhold. pp. 1554.).


Ethylenediamine (EDA) is a clear and colorless product at normal temperature and pressure which has a characteristic smell of an amine. It is strongly alkaline and is miscible with water and alcohol. It is air sensitive and hygroscopic and absorbs carbon dioxide from the air. It is incompatible with aldehydes, phosphorus halides, organic halides, oxidising agents, strong acids, copper, its alloys, and its salts.

Health Hazard

Vapor inhalations at a concentration of 200 ppm for 5 to 10 minutes will lead to nasal irritation and produce a tingling sensation. Inhalation at concentrations of 400 ppm or greater leads to severe nasal irritation. Respiratory irritation may result. Many individuals are hypersensitive to Ethylenediamine exposure; therefore, safe threshold limits are difficult to set.

Purification Methods

It forms a constant-boiling (b 118.5o, monohydrate, m 10o) mixture with water (23w/w%). [It is hygroscopic and miscible with water.] Recommended purification procedure [Asthana & Mukherjee in J.F.Coetzee (ed), Purification of Solvents, Pergamon Press, Oxford, 1982 cf p 53]: to 1L of ethylenediamine is added 70g of type 5A Linde molecular sieves and shaken for 12hours. The liquid is decanted and shaken for a further 12hours with a mixture of CaO (50g) and KOH (15g). The supernatant is fractionally distilled (at 20:1 reflux ratio) in contact with freshly activated molecular sieves. The fraction distilling at 117.2o /760mm is collected. Finally it is fractionally distilled from sodium metal. All distillations and storage of ethylenediamine should be carried out under nitrogen to prevent reaction with CO2 and water. The material containing 30% water is dried with solid NaOH (600g/L) and heated on a water bath for 10hours. Above 60o, separation into two phases takes place. The hot ethylenediamine layer is decanted off, refluxed with 40g of sodium for 2hours and distilled [Putnam & Kobe Trans Electrochem Soc 74 609 1938]. Ethylenediamine is usually distilled under nitrogen. Alternatively, it is dried over type 5A Linde molecular sieves (70g/L), then a mixture of 50g of CaO and 15g of KOH/L, with further dehydration of the supernatant with molecular sieves followed by distillation from molecular sieves and, finally, from sodium metal. A spectroscopically improved material is obtained by shaking with freshly baked alumina (20g/L) before distillation. [Beilstein 4 IV 1166.]


ChEBI: An alkane-alpha,omega-diamine in which the alkane is ethane.

Fire Hazard

Burning rate: 2.2 mm/minute. When exposed to heat or flame, the material has a moderate fire potential. The material can react readily with oxidizing materials. Containers may explode in heat of fire. Material emits nitrogen oxides when burned. Avoid carbon disulfide, silver perchlorate, imines, oxidizing materials. Stable. Hazardous polymerization may not occur.

Air & Water Reactions

Highly flammable. Hygroscopic. Fumes in the air. Water soluble. Biodegrades readily.


[Note—Edamine is the recommended contraction for the ethylenediamine radical.].


[1] Formation of metal complexes with ethylenediamine: a critical survey of equilibrium constants, enthalpy and entropy values, Pure & Applied Chemistry, vol. 56, 1984, pp.491-522
[2] K. Segawa, S. Mizuno, M. Sugiura, S. Nakata, Selective synthesis of ethylenediamine from ethanolamine over modified H-mordenite catalyst, Studies in Surface Science and Catalysis, vol. 101, 1996, pp. 267-276
[3] https://en.wikipedia.org/wiki/Ethylenediamine
[4] Norbert Rietbrock, B. G. Woodcock, A. H. Staib, Theophylline and other Methylxanthines, 1981, ISBN 978-3-663-05269-2
[5] Ian A. Cotgreave, John Caldwell, Comparative plasma pharmacokinetics of theophylline and ethylenediamine after the administration of aminophylline to man, Journal of Pharmacy and Pharmacology, vol. 35, 1983, pp. 378-382
[6] http://www.heraproject.com/files/2-f-04-hera%20taed%20full%20web%20wd.pdf
[7] http://product-finder.basf.com/group/corporate/product-finder/en/brand/ETHYLENEDIAMINE

Chemical Properties

CLEAR liquid


Ethylenediamine can be synthesized from ethanolamine (EA) with ammonia over acidic types of zeolite catalyst.2 It is produced industrially by the reaction of 1,2-dichloroethane with ammonia in a liquid base under high temperature and high presseure.3 The synthesis of ethylenediamine from 1,2-dichloroethane is ClCH2CH2Cl + 2NH3 → NH2CH2CH2NH2*2HCl
Nevertheless, there are too many byproducts during the reaction. The key of this synthesis is to improve the selectivity of reaction product and the application of advanced separation methods to obtain high product purity.

Contact allergens

Ethylenediamine is used in numerous industrial processes as a solvent for casein or albumin, as a stabilizer in rubber latex, and as a textile lubricant. It can be found in epoxy resin hardeners, cooling oils, fungicides, and waxes. Contact dermatitis from ethylenediamine is almost exclusively due to topical medicaments. Occupational contact dermatitis in epoxy resin systems is rather infrequent. Ethylenediamine can crossreact with triethylenetetramine and diethylenetriamine. Ethylenediamine was found to be responsible for sensitization in pharmacists handling aminophylline suppositories, in nurses preparing and administering injectable theophylline, and in a laboratory technician in the manufacture of aminophylline tablets


Ligands in coordination chemistry
With the two nitrogen atoms, which can donate their lone pairs of electrons, ethylenediamine is widely used as a chelating ligand for coordination chemistry to form bonds to a transition-metal ion such as nickel (II).3 The bonds form between the metal ion and the nitrogen atoms of ethylenediamine. Ethylenediaminetetraacetic acid (EDTA) is a derivate of ethylenediamine and it is a versatile chelating agent, which could form chelates with both transition-metal ions and main-group ions. Ethylenediamine is mainly used to synthesize ethylenediaminetetraacetic acid. EDTA is frequently used in soaps and detergents to form complexes with calcium and magnesium ions in hard water to improve the cleaning efficiency. Furthermore, EDTA is used extensively as a stabilizing agent in the food industry to promote color retention, to improve flavor retention, and to inhibit rancidity.

Pharmaceutical ingredient
Ethylenediamine is used to facilitate the dissolution of theophylline. This combination is known as aminophylline and used to treat and prevent wheezing and trouble breathing caused by ongoing lung disease (e.g. asthma, emphysema, chronic bronchitis).4 It is evidenced that there is no molecular association between theophylline and ethylenediamine in biological media. The bioavailability of ethylenediamine is approximately 34% and of theophylline is about 88%.5

Ethylenediamine is used as an intermediate in the manufacture of tetraacetyl ethylenediamine (TAED), a bleaching activator, which is used in detergents and additives for laundry washing and dishwashing.6 The amount of TAED used in household cleaning products in Europe was estimated to be 61,000 t in 2001.

Other applications
Ethylenediamine is in the manufacture of organic flocculants, urea resins, and fatty bisamides. It is used in the production of formulations for use in the printed circuit board and metal finishing industries. It is used as intermediate in the production of crop protection agents, hardeners for epoxy resins, leather industry, paint industry, fungicides in crop protection area, and textile industry.7 Ethylenediamine is also used as solvent and for the analytical chemistry. It is used to produce photographic fixer additive

107-15-3 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
Aldrich (15068)  Ethylenediaminesolution  technical, 75-80% 107-15-3 15068-190L 41,675.40CNY Detail
Aldrich (15068)  Ethylenediaminesolution  technical, 75-80% 107-15-3 15068-1L 755.82CNY Detail
Aldrich (391085)  Ethylenediamine  purified by redistillation, ≥99.5% 107-15-3 391085-1L 5,720.13CNY Detail
Aldrich (391085)  Ethylenediamine  purified by redistillation, ≥99.5% 107-15-3 391085-100ML 1,187.55CNY Detail
Sigma (E1521)  Ethylenediamine  BioXtra 107-15-3 E1521-1L 1,463.67CNY Detail
Sigma (E1521)  Ethylenediamine  BioXtra 107-15-3 E1521-250ML 593.19CNY Detail
Sigma-Aldrich (41008)  Ethylenediamine  analytical standard 107-15-3 41008-1ML-F 265.59CNY Detail
Sigma-Aldrich (03550)  Ethylenediamine  puriss. p.a., absolute, ≥99.5% (GC) 107-15-3 03550-2.5L 3,944.07CNY Detail
Sigma-Aldrich (03550)  Ethylenediamine  puriss. p.a., absolute, ≥99.5% (GC) 107-15-3 03550-1L 1,903.59CNY Detail
Sigma-Aldrich (03550)  Ethylenediamine  puriss. p.a., absolute, ≥99.5% (GC) 107-15-3 03550-250ML 769.86CNY Detail
Alfa Aesar (A12132)  Ethylenediamine, 99%    107-15-3 10000ml 3428.0CNY Detail
Alfa Aesar (A12132)  Ethylenediamine, 99%    107-15-3 2500ml 947.0CNY Detail



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017


1.1 GHS Product identifier

Product name ethylenediamine

1.2 Other means of identification

Product number -
Other names 1.2-Diamino-dekan

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Agricultural chemicals (non-pesticidal),Corrosion inhibitors and anti-scaling agents,Functional fluids (closed systems),Intermediates,Ion exchange agents,Lubricants and lubricant additives,Paint additives and coating additives not described by other categories
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:107-15-3 SDS

107-15-3Related news

Stepwise pretreatment of aqueous ammonia and Ethylenediamine (cas 107-15-3) improve enzymatic hydrolysis of corn stover08/20/2019

It is a trade-off between sugar loss in pretreatment and sugar release in hydrolysis for most pretreatment. Here, a stepwise mild pretreatments of aqueous ammonia pretreatment and ethylenediamine was developed to reduce the sugar loss during pretreatment process and improve the sugar release in ...detailed

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